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Ripe fruit of Rubus coreanus inhibits mast cell-mediated allergic inflammation.

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In this study, we investigated the effect of a water extract of the ripe fruits of Rubus coreanus Miq. (Rosaceae) (RFRC) on mast cell-mediated allergic inflammation and studied the possible mechanism of action. Mast cell-mediated allergic disease is involved in many diseases such as anaphylaxis,

Black Raspberries and Protocatechuic Acid Mitigate DNFB-Induced Contact Hypersensitivity by Down-Regulating Dendritic Cell Activation and Inhibiting Mediators of Effector Responses

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Contact hypersensitivity (CHS) is the most common occupational dermatological disease. Dendritic cells (DCs) mediate the sensitization stage of CHS, while T-cells facilitate the effector mechanisms that drive CHS. Black raspberry (Rubus occidentalis, BRB) and BRB phytochemicals possess

A randomized, double-blind, placebo-controlled study of ten-cha (Rubus suavissimus) on house dust mite allergic rhinitis.

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OBJECTIVE Self-care with ten-cha is the most common complementary alternative medicine for allergic rhinitis in Japan, but evidence for an actual therapeutic effect is lacking. The purpose of the study was to investigate the effect of ten-cha (Rubus suavissimus) on house dust mite allergic

Contact allergy to styrene and related chemicals.

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One patient, sensitive to styrene, cross-reacted at patch testing to 2-,3-and 4-vinyltoluene (2-,3-and 4-methylstyrene) and to the metabolites styrene epoxide and 4-vinylphenol (4-hydroxy-styrene). It is assumed that styrene is a prohapten metabolized in the skin by aryl hydrocarbon hydroxylase

[Anti-allergic effects of Rubus suavissimus extract].

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OBJECTIVE To investigate the effects of Rubus suavissimus S. Lee extract (RSE) on mice, and its influence on release of histamine from rat peritoneal mast cells induced by compound 48/80 in vitro. METHODS To establish murine delayed-type-hypersensitive model induced by 2,4-dinitrofluotobenzene

Antiinflammatory activities of Rubus coreanus depend on the degree of fruit ripening.

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The dried unripe fruit of Rubus coreanus, which is well-known in Korea and referred to as 'Bok-bun-ja', has been employed as a traditional medicine for centuries. This crude drug is utilized in Korea for the management of impotence, spermatorrhea, enuresis, asthma and allergic diseases. The

Stevens-Johnson syndrome secondary to ingestion of salmon berries.

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Stevens-Johnson syndrome is an immune mucocutaneous disorder which can follow viral infections, mycoplasma infections and the ingestion of some drugs. There is also evidence supporting this disease as a hypersensitivity disorder. We observed a four-year-old girl with Stevens-Johnson syndrome

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