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Urea for hyponatraemia due to the syndrome of inappropriate antidiuretic hormone secretion.

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Hyponatraemia due to the syndrome of inappropriate antidiuretic hormone secretion (SIADH) can pose a therapeutic challenge. After fluid restriction, urea is recommended as a second-line treatment by Dutch and European treatment guidelines. Data on this practice are still scarce. We

Treatment of nausea and vomiting in pregnancy. When should it be treated and what can be safely taken?

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Nausea and vomiting are both common in early pregnancy. Most cases are mild and do not require treatment. However, persistent vomiting and severe nausea can progress to hyperemesis if the woman is unable to maintain adequate hydration, and fluid and electrolyte as well as nutritional status are

Intra-amniotic prostaglandin F2alpha and urea for midtrimester abortion.

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Intra-amniotic prostaglandin F2alpha, in doses of 2.5 to 20 mg, combined with 80 gm of urea, was an effective, safe, simple, and economical midtrimester abortifacient in 115 patients. The mean abortal time, 15.8 hours, was significantly less than that in prior series in which intra-amniotic

Self-reported treatment-associated symptoms among patients with urea cycle disorders participating in glycerol phenylbutyrate clinical trials.

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BACKGROUND Health care outcomes have been increasingly assessed through health-related quality of life (HRQoL) measures. While the introduction of nitrogen-scavenging medications has improved survival in patients with urea cycle disorders (UCDs), they are often associated with side effects that may

[Diagnosis and treatment of urea cycle disorders in adult patients].

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Urea cycle disorders (UCDs) are inborn errors of metabolism in which the clinical picture is mostly due to ammonia intoxication. UCD onset may be observed at any age. Acute decompensations of UCDs include neuro-psychiatric symptoms such as headache, confusion, convulsions, ataxia, agitation or

Intraamniotic urea for induction of midtrimester pregnancy termination: a further evaluation.

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Forty percent hyperosmolar urea solution was used intraamniotically to induce midtrimester pregnancy termination in 508 patients. The mean injection-abortion interval was 43.4 hours in those patients aborting within 7 days (85.8% of the total group); 76% of the group aborted within 72 hours.

Carbon-13 urea breath test for Helicobacter pylori infection in patients with uninvestigated ulcer-like dyspepsia: an evidence-based analysis.

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BACKGROUND Dyspepsia is a condition defined by chronic pain or discomfort in the upper gastrointestinal tract that can be caused by Helicobacter pylori. The carbon-13 urea breath test (¹³C UBT) is a non-invasive test to detect H. pylori. OBJECTIVE We aimed to determine the diagnostic accuracy and

Intravascular spill of hyperosmolar urea during induced midtrimester abortion.

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Intravascular spill of hypertonic sodium chloride and the resultant serious and occasionally fatal consquences have been reported in association with induced midtrimester abortion. This report details 3 cases of intravascular spill of hyperosmolar urea. Although urea may pose less concern, because

Elevated phenylacetic acid levels do not correlate with adverse events in patients with urea cycle disorders or hepatic encephalopathy and can be predicted based on the plasma PAA to PAGN ratio.

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BACKGROUND Phenylacetic acid (PAA) is the active moiety in sodium phenylbutyrate (NaPBA) and glycerol phenylbutyrate (GPB, HPN-100). Both are approved for treatment of urea cycle disorders (UCDs) - rare genetic disorders characterized by hyperammonemia. PAA is conjugated with glutamine in the liver

Effect of lysine infusion on urea cycle in lysinuric protein intolerance.

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Poor intestinal absorption and excessive renal loss of dibasic amino acids result in low plasma concentrations in patients with lysinuric protein intolerance (LPI). Arginine and ornithine deficiency impair the function of the urea cycle and cause hyperammonemia after protein intake, while chronic

Nausea and high serum osmolality during a simulated ultraendurance adventure race: a case-control study.

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OBJECTIVE A 29-year-old elite adventure-race athlete presented with a 10-month history of nausea appearing during or after ultraendurance races. The athlete noted recent worsening of symptoms, including lightheadedness, dark rings under the eyes, and weakness as nausea became worse, and was unable

Poisoning due to urea herbicides.

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Urea herbicides, which act by inhibiting photosynthesis, were introduced in 1952 and are now used as pre- and post-emergence herbicides for general weed control in agricultural and non-agricultural practices. Urea herbicides are generally of low acute toxicity and severe poisoning is only likely

Blood tests for investigating maternal wellbeing. 4. When nausea and vomiting in pregnancy becomes pathological: hyperemesis gravidarum.

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Nausea and vomiting in pregnancy (NVP) is commonplace, with many midwives frequently counselling women in their care. But how do midwives know when NVP becomes pathological? Although hyperemesis gravidarum (HEG) is less common, midwives must be able to recognise and differentiate between these two

Oral manifestations and analysis of salivary and blood urea levels of patients under going haemo dialysis and kidney transplant.

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OBJECTIVE To evaluate oral manifestations in patients with renal diseases and to correlate blood and salivary urea levels in patients undergoing haemodialysis and kidney transplant. METHODS Study group subjects were selected from patients undergoing hemodialysis and patients who had underwent kidney

A Case of Atypical Adult Presentation of Urea Cycle Disorder.

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Urea cycle disorders are metabolic disorders of nitrogenous waste substances due to either complete or partial deficiency of enzymes. Hyperammonemia associated with urea cycle disorders should be addressed immediately in the acute setting, as it can cause irreversible neurological

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