DAPHNE Scale Validation in Frontotemporal Lobar Degeneration
Cuvinte cheie
Abstract
Descriere
Psycho-behavioral disorders assessment is crucial for the diagnosis and follow-up of patients with frontotemporal degeneration (FTD). DAPHNE scientific staff have therefore developed a quantification and follow-up scale specifically dedicated to patients with FTD in current clinical practice. This scale is called DAPHNE to Disinhibition, Apathy, Perseveration, Hyperorality, Negligence and loss of Empathy. This study aims to validate this scale. This validation will include methodological steps required to develop a new clinical tool, by studying internal consistency, loyalty, and concurrent validity in comparison with validated existing tools. Complementarily, sensitivity and specificity will be assessed via a control population including patients with Alzheimer's disease, , progressive supranuclear palsy and bipolar disorder with cognitive disorders.
Datele
| Ultima verificare: | 07/31/2017 |
| Primul depus: | 08/23/2016 |
| Inscriere estimată trimisă: | 08/29/2016 |
| Prima postare: | 09/04/2016 |
| Ultima actualizare trimisă: | 08/15/2017 |
| Ultima actualizare postată: | 08/20/2017 |
| Data actuală de începere a studiului: | 01/31/2013 |
| Data estimată de finalizare primară: | 12/30/2013 |
| Data estimată de finalizare a studiului: | 12/30/2015 |
Stare sau boală
Intervenție / tratament
Other: Psycho-behavioural assessment
Fază
Grupuri de brațe
| Braţ | Intervenție / tratament |
|---|---|
| Fronto-temporal lobar degeneration DAPHNE score building and internal validation through Fronto-temporal lobar degeneration patients. | |
| Control External validation of DAPHNE score among patients with Alzheimer's disease, progressive supranuclear palsy and bipolar disorder with cognitive disorders. |
Criterii de eligibilitate
| Vârste eligibile pentru studiu | 18 Years La 18 Years |
| Sexe eligibile pentru studiu | All |
| Metoda de eșantionare | Non-Probability Sample |
| Acceptă voluntari sănătoși | da |
| Criterii | Inclusion Criteria: Group 1: 1. Patients with FTD according Neary (1998) and Raskowsky (2011) diagnostic criteria. 2. Mini-Mental State Examination ≥ 18 3. Consent Group 2 Control: 1. Patients with Alzheimer's disease (MacKahn, 2011), patients with supranuclear palsy (Litvan, 1996) and patients with bipolar disorder with cognitive disorders. criteria. 2. Mini-Mental State Examination ≥ 18 3. Consent Exclusion Criteria: - Minor patient |
Rezultat
Măsuri de rezultate primare
1. Internal validation of DAPHNE Score [Baseline]
