Zhongguo Zhongyao Zazhi 2009-Jul
[Chemical constituents from Xanthium mongolicum].
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Abstract
OBJECTIVE
To study the chemical constituents of Xanthium mongolicum.
METHODS
The compounds were isolated with column chromatography. The structures were determined by spectroscopic techniques.
RESULTS
Eight compounds were isolated from X. mongolicum, four compounds are sesquiterpene lactones, two compounds are triterpenes and two compounds are lignins. Their structure elucidated as xanthatin (1), xanthinosin (2), 11alpha, 13-dihydroxanthatin (3), atractylenolide III (4), oleanolic acid (5), ursolic acid (6), lignocellulose (7), balanophonin (8).
CONCLUSIONS
Compounds 3-8 were isolated from this plant for the first time. Sesquiterpene lactones (1-3) had shown the induction hindrance activeness of the (ICAM-1), but the activitiy of 3 was weaker.
