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Local treatment of necrotizing scleritis with cyclosporin A.
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Abstract
A report is presented on an 83-year-old female patient with seropositive rheumatoid arthritis who developed a necrotizing scleritis of the right eye. The clinical course could not be influenced by indomethacin, cysteine, and the cytostatic chlorambucil. Local cyclosporin treatment, however, which was initiated after a 4-week therapy-free period, led to considerable improvement within a few days. The disease disappeared after 6 weeks of treatment. There is no recurrence as yet, the follow-up period being 13 months.
