Open Access Macedonian Journal of Medical Sciences 2019-Nov

Cytoprotective Activity of Ethylacetate Fraction of Picria fel-terrae Lour. Herbs.

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Denny Satria

Jansen Silalahi

Ginda Haro

Syafruddin Ilyas

Poppy Hasibuan

ARTICOL: 32127993

DOI: 10.3889/oamjms.2019.521

PMC: PMC7048334

BioSeek: 32127993

Cuvinte cheie

Abstract

AIM

Free radicals produce from metabolism or enviromental which interact continously with biological system. Picria fel-terrae Lour. herbs have been used as antioxidant and treat various diseases. The aim of this study was to evaluate cytoprotective activity of ethylacetate fraction (EAF) of Picria fel-terrae Lour. herbs.

METHODS

Cytoprotective activity were determined by MTT asay and flow cytometry assay on Vero cells which induced with H₂O₂ 0.8 mM.

EAF at 100 µg/mL were showed highest viability (88.83 ± 2.90%) and ROS expression (66.75%) on Vero cells.

CONCLUSION

EAF of Picria fel-terrae Lour. herbs have cytoprotective activity.

Cytoprotective Activity of Ethylacetate Fraction of Picria fel-terrae Lour. Herbs.

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picria

listă de antioxidanți

Abstract

Cea mai completă bază de date cu plante medicinale susținută de știință