anemia/bactericid

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Iron deficiency: beyond anemia.

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Iron deficiency is the most common nutritional disorder affecting at least one third of world's population. Though anemia is common manifestation of iron deficiency, other effects of iron deficiency on various tissues, organs and systems are usually under recognized. Impaired brain development and

Drug-induced fatal aplastic anemia following cataract surgery.

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Aplastic anemia attributed to medications used in ophthalmology is rare. We report a fatal case that developed in a 73-year-old woman 7 weeks after cataract extraction performed under local anesthesia. Postoperative medications included a chloramphenicol-containing ointment, flurbiprofen sodium

[Sickle cell anemia and functional asplenia (author's transl)].

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On the occasion of 34 spleen scintigrams performed in children with sickle cell anemia, the frequency and precocity of the "functional asplenia" is emphasized and its relationship with the infectious history of such children is discussed. The anti-bacterial role of the spleen and the responsibility,

Hemolytic Anemia and Reactive Thrombocytosis Associated With Cefoperazone/Sulbactam.

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Background: Cefoperazone/sulbactam is a broad-spectrum antibacterial agent. Drug-induced immune hemolytic anemia is a rare but serious condition, and reactive thrombocytosis is caused by processes extrinsic to the megakaryocyte. Limited data are available for cefoperazone/sulbactam-associated

Neutrophil dysfunction in the rabbit model of spur cell anemia.

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In the rabbit model for spur cell anemia, animals fed a 5% cholesterol diet develop marked hypercholesterolemia and hemolytic spur cell anemia after several weeks on the diet. In vitro tests of granulocytes showed a 15% increase in cholesterol: phospholipid ratio, and decreased membrane fluidity

Chlorinated urban water: a cause of dialysis-induced hemolytic anemia.

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Unexplained acute hemolytic anemia is sometimes seen in uremic patients undergoing hemodialysis. Chloramines, which are oxidant compounds made up of chlorine and ammonia and are widely used as bactericidal agents in urban water supplies, have been found responsible for two recent epidemics, in

Effects of chicken anemia virus on macrophage function in chickens.

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One-day-old chicks were inoculated intramuscularly with chicken anemia virus (CAV). Four birds were killed at 7, 14, 21, 28, and 42 days postinoculation (PI), and macrophages were recovered from spleen and bone-marrow suspensions. These were tested for interleukin-1 (IL-1) production, Fc receptor

[Anemia during inflammatory processes: pathogenesis and clinical and morphological manifestations].

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The review sums up the results of the current stage of studying the so-called anemia of inflammation (AI). The key mediator of AI is the polypeptide hepatic hormone hepcidin, the hepatocytic secretion of which is initiated by proinflammatory macrophageal cytokines (IL-6, IL-lalpha, and tumor

Hepcidin and anaemia.

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The anaemia of chronic disease (ACD) is a common haematologic syndrome characterized by hypoferraemia with adequate reticuloendothelial iron stores. Frequently, serum ferritin concentration in these patients is elevated. The pathogenesis of ACD involves abnormalities in red cell survival, the

A Case of Aplastic Anemia Associated With Long-Term Metronidazole Use.

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Metronidazole is a nitroimidazole antibacterial agent that is highly effective for the treatment of protozoal and anaerobic infections. Metronidazole is known to cause hematologic adverse effects, including a reversible mild neutropenia; in rare circumstances, thrombocytopenia has been associated

Neutrophil gelatinase-associated lipocalin (NGAL): a new piece of the anemia puzzle?

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Neutrophil Gelatinase-Associated Lipocalin (NGAL), a small 25-kD peptide, originally discovered as an antibacterial factor of natural immunity and an acute-phase protein, represents a key factor in the regulation of erythrocyte growth due to its ability to inhibit the maturation and differentiation

Anaemia and immune response.

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Nutritional anaemia is a major public-health problem in many parts of the world, and iron deficiency appears to be the most important cause. The immune response is believed to be impaired in anaemia. The results of the present study, carried out in young children, indicate that both the

[Evaluation of phagocytic and bactericidal activities of neutrophils in peripheral blood of patients with anemia due to iron deficit].

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Phagocytic and bactericidal properties of neutrophils have been evaluated in 20 women with anemia due to iron deficit. Twenty healthy women in corresponding age and domicile served as a control group. No statistically significant difference in both phagocytic and bactericidal properties of

Compliance with antibiotic prophylaxis in children with sickle cell anemia: a prospective study.

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OBJECTIVE To prospectively assess compliance with antibiotic prophylaxis among children with sickle cell anemia. METHODS A total of 108 children (aged 3 months to 4(1/2) years, 45% male) were recruited from the Hematology Center in Belo Horizonte, Brazil, and followed up for 15 months. Data on

Hepcidin and cytokines in anaemia.

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Hepcidin is a cytokine-induced antibacterial protein which is produced in the liver, circulates in the blood, and is excreted in the urine. It is a major regulator of iron balance in the intestinal mucosa, and appears to have a significant role in the pathogenesis of haemochromatosis and related

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