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anemia/cancer mamar

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[Hemolytic anemia associated with breast neoplasm].

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We describe a patient with a microangiopathic hemolytic anemia, associated with thrombocytopenia, in consequence of breast cancer in an advanced phase. Microangiopathic hemolytic anemia is a rare and serious compliance of malignant neoplasms, in particular of breast and gastric carcinomas.

Mutated Fanconi anemia pathway in non-Fanconi anemia cancers.

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An extremely high cancer incidence and the hypersensitivity to DNA crosslinking agents associated with Fanconi Anemia (FA) have marked it to be a unique genetic model system to study human cancer etiology and treatment, which has emerged an intense area of investigation in cancer research. However,

Fanconi anemia and breast cancer susceptibility.

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[Hemolytic anemia in metastatic breast cancer].

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[Microangiopathic hemolytic anemia associated with breast cancer].

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A case of microangiopathic hemolytic anemia associated to metastatic breast cancer, in remission with chemotherapy, is presented. We review the etiopathogenetic mechanism of its association and focus on the priority of neoplasia therapy when disseminated intravascular coagulation is not present.
Hemolytic anemia in the setting of malignancy is a rare manifestation of paraneoplastic syndrome with significant morbidity. Here we discuss a case involving metastatic breast cancer presenting with severe hemolytic anemia and renal failure secondary to thrombotic microangiopathy of malignancy. This

[Microangiopathic hemolytic anemia associated with breast cancer].

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Fanconi anemia and breast cancer susceptibility meet again.

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A new study reports biallelic mutations in RAD51C in a Fanconi anemia-like disorder, while a second study reports monoallelic mutations in the same gene associated with increased breast cancer risk. These findings strengthen the link between Fanconi anemia and breast cancer-associated pathways.

Fanconi anemia and breast cancer: what's the connection?

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Recurred breast cancer presenting with autoimmune hemolytic anemia.

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Susceptibility pathways in Fanconi's anemia and breast cancer.

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Breast cancer and Fanconi anemia: what are the connections?

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Surprisingly, biallelic mutations in the BRCA2 breast-cancer-susceptibility gene were found in Fanconi anemia (FA), a rare hereditary disorder characterized by chromosomal instability, hypersensitivity to DNA cross-linking agents, and cancer susceptibility. This suggests that a defect in the FA

Iron homeostasis and anemia markers in early breast cancer.

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Iron plays a fundamental role in cell life and its concentration in living organisms is precisely regulated. Different molecules for iron storage and transport are used to maintain its intracellular homeostasis which is often altered in cancer cells. Specifically, recent studies have demonstrated

Evaluation of Fanconi Anemia genes in familial breast cancer predisposition.

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Fanconi Anemia (FA) is an autosomal recessive syndrome characterized by congenital abnormalities, progressive bone marrow failure, and susceptibility to cancer. FA has eight known complementation groups and is caused by mutations in at least seven genes. Biallelic BRCA2 mutations were shown recently

Metastatic breast cancer manifested as refractory anemia and gastric polyps.

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Gastric metastasis from breast cancer is uncommon and typically occurs in patients with disseminated disease. The vast majority of patients with gastric lesions have a known preexisting diagnosis of breast cancer. In contrast, we describe a case in which a minimal breast cancer was found to be the
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