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Antiproliferative activity and apoptosis induction, of organo-antimony(III)-copper(I) conjugates, against human breast cancer cells.

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Three known organo-antimony(III)-copper(I), mixed-metal small bioactive molecules (SBAMs) of formula [Cu(tpSb)₃Cl] (1), [Cu₂(tpSb)₄Br₂] (2) and [Cu₂(tpSb)₄I₂] (3) (tpSb = triphenylstibine) were used for the clarification of

Chest X-ray Artifact Caused by Bilateral 99mTc-Antimony Trisulfite Injection for Sentinel Node Imaging in a Patient With Breast Cancer.

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A 52-year-old woman diagnosed with invasive ductal carcinoma of both breasts had a chest x-ray for preoperative assessment. A striking artifact was noted by the x-ray technologist, who, as a result, became very concerned about radiation exposure from the patient. The patient had undergone bilateral

Plasma micronutrients, trace elements, and breast cancer in BRCA1 mutation carriers: an exploratory study.

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OBJECTIVE Few studies have evaluated the role of micronutrients or trace elements in breast cancer development among BRCA1 mutation carriers. To investigate a possible role of dietary and environmental exposures on cancer risk, we undertook an exploratory study, using a matched case-control design

Nanotoxicology and Metalloestrogens: Possible Involvement in Breast Cancer.

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As the use of nanotechnology has expanded, an increased number of metallic oxides have been manufactured, yet toxicology testing has lagged significantly. Metals used in nano-products include titanium, silicon, aluminum, silver, zinc, cadmium, cobalt, antimony, gold, etc. Even the noble metals,

Clinically node-negative breast cancer, internal mammary lymph nodes, and sentinel lymph node biopsy.

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We report 2 cases demonstrating that localization of internal mammary (IM) sentinel lymph nodes with lymphoscintigraphy using peritumoral injection of Tc-99m antimony sulfide colloid, followed by resection using minimal access surgery, can reveal nodal metastatic disease in patients with clinically

Same-day lymphoscintigraphy and sentinel node biopsy for early breast cancer.

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BACKGROUND Lymphoscintigraphy and sentinel node biopsy are currently being assessed as an alternative to axillary dissection for staging in early breast cancer. However, little is known about the optimum timing of surgery following injection of the radio-isotope into the breast. The aim of the

Factors influencing the time of sentinel node visualization in breast cancer patients using intradermal injection of the radiotracer.

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BACKGROUND The objective of our study was to determine the important factors that have influence on the time of sentinel node visualization using intradermal injection of (99m)Tc-antimony sulfide colloid. METHODS Two hundred fifty consecutive patients with the diagnosis of early-stage breast cancer

NADINE: new approaches to detecting breast cancer by sequential μm-wavelength imaging with the aid of novel frequency analysis techniques.

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The study focuses on 12 breasts of six breast cancer patients sequential µm-wavelength imaging, taken by two different 3-5 μm wavelength area indium antimony (InSb) photovoltaic cameras. The aim of the study was to compare the functionality of area and pixel-based frequency analyses. Comparisons

Factors affecting sentinel lymph node detection failure in breast cancer patients using intradermal injection of the tracer.

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OBJECTIVE The standard method for axillary lymph node staging in early breast cancer is sentinel lymph node biopsy. In some patients the sentinel lymph node can not be localized during surgery and these patients have to undergo standard axillary lymph node dissection. In this study we have evaluated

The effect of excisional biopsy on the accuracy of sentinel lymph node mapping in early stage breast cancer: comparison with core needle biopsy.

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Despite the successful application of sentinel node mapping in breast cancer patients, its use in patients with a history of previous excisional biopsy of the breast tumors is a matter of controversy. In the present study we evaluated the accuracy of sentinel node biopsy in this group of patients

Predicting nodal metastases in breast cancer by lymphoscintigraphy.

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In a prospective trial, 89 women with breast lumps underwent bilateral axillary and internal mammary lymphoscintigraphy preoperatively, using technetium-99m antimony sulfide colloid. All scans were interpreted blindly by three separate observers. Breast biopsy was then performed; if the biopsy

Efficacy of high-energy collimator for sentinel node lymphoscintigraphy of early breast cancer patients.

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BACKGROUND Lymphoscintigraphy is an important part of sentinel node mapping in breast cancer patients. Sometimes star shaped artefacts due to septal penetration can be problematic during imaging. In the current study, we evaluated the possibility of high energy (HE) collimators use for

Analysis of sentinel nodes biopsy in breast cancer--12 years after introduction into clinical practice.

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BACKGROUND Sentinel node biopsy in breast cancer has been a standard procedure at the Institute for Oncology of Vojvodina since 1999 and we have done more than 700 biopsy. Before the introduction of axillary sentinel lymph node biopsy, lymph nodes were routinely dissected, and this approach was the

Prospective Randomized Trial of Use of In-House Prepared Low-Cost Radiopharmaceutical Versus Commercial Radiopharmaceutical for Sentinel Lymph Node Biopsy in Patients with Early Stage Invasive Breast Cancer.

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The current standard-of-care for surgical staging of the axilla in clinically node-negative (N0) early breast cancers is sentinel lymph node biopsy (SLNB), which requires expensive radiopharmaceuticals for efficacious results. In-house produced low-cost radiopharmaceuticals may be the solution and

Comparison of early and delayed lymphoscintigraphy images of early breast cancer patients undergoing sentinel node mapping.

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OBJECTIVE We compared early and delayed lymphoscintigraphy images using intradermal injection of (99m)Tc-antimony sulfide colloid, which has small particles. METHODS Eighty patients with early-stage breast cancer were included into the study. Intradermal injection of (99m)Tc-antimony sulfide colloid

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