The Haptoglobin 2-2 group randomised to Vitamin E

The Haptoglobin 2-2 group randomised to placebo

The Non Haptoglobin 2-2 group randomised to Vitamin E

The Non Haptoglobin 2-2 group randomised to placebo

Diabetes Mellitus

Two hundred patients will be recruited to a pilot randomized controlled trial (RCT), stratified by Hp 2-2 phenotype status (100 Hp 2-2 and 100 non-Hp 2-2), and randomly allocated in a 1:1 ratio to either vitamin E 400 IU supplementation daily for 6 months or a placebo group. The trial will determine whether vitamin E improves the aforementioned surrogate markers in the Hp phenotype strata.

Vitamin E

Placebo

Tan Tock Seng Hospital

Relationship of Haptoglobin Phenotype to Vascular Function and Response to Vitamin E Supplementation in Patients With Diabetes Mellitus Type 2: The EVAS Trial

Measured as Reactive hyperemia index using RHI-EndoPAT

Measured as pulse wave velocity using the sphygmocor device

Measured as ratio between retinal arterial diameter and venous diameter as retinal AV index

Lee Kong Chian School of Medicine, Nanyang Technological University

National Medical Research Council (NMRC), Singapore

Active Arm:
1000 mg Lemon flavored Capsules. Three capsules every morning.

Placebo Arm:
Cornstarch Capsules provided by Clinical Encapsulation services. Three capsules every morning.

Coronary Artery Disease

Inflammatory Response

Atherosclerosis

three capsules daily (1350 mg daily) of EPA for 8 weeks or three capsules daily placebo for 8 weeks

eicosapentaenoic acid (EPA),

Cleveland Clinic Willoughby Hills Family Health Center

Trial to Study the Effects of Supplementary Omega-3 on Serum C-Reactive Protein Levels

Protocol for a Randomized, Placebo-Controlled, Double-Blinded Trial to Study the Effects of Supplementary Omega-3 Fatty Acids on Serum C-Reactive Protein Levels

d alpha tocopherol/inflamație

Relationship of Haptoglobin Phenotype to Vascular Function and Response to Vitamin E Supplementation in Patients With Diabetes Mellitus Type 2: The EVAS Trial

Trial to Study the Effects of Supplementary Omega-3 on Serum C-Reactive Protein Levels

Cea mai completă bază de date cu plante medicinale susținută de știință