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dasymaschalon trichophorum/alkaloid

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ArticoleStudii cliniceBrevete
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Cytotoxic and Antimalarial Alkaloids from the Twigs of Dasymaschalon obtusipetalum.

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One new p-quinonoid aporphine alkaloid, obtusipetadione (1), and eleven known compounds (2-12) were isolated from the acetone extract of the twigs of Dasymaschalon obtusipetalum. Their structures were elucidated by spectroscopic methods. The cytotoxic and antimalarial activities of the isolated

Bioactive aporphine alkaloids from the stems of Dasymaschalon rostratum.

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Three undescribed aporphine alkaloids dasymaroine A (1), 3-methoxyoxoputerine N-oxide (2), and dasymaroine B (3), along with nine known analogues (4-12) were isolated from the stems of Dasymaschalon rostratum Merr. The structures were elucidated using spectroscopic methods and by comparison with

Cytotoxic alkaloids from leaves and twigs of Dasymaschalon sootepense.

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Bioassay-guided fractionation of the cytotoxic ethyl acetate fraction of the sequential methanol extract from the leaves and twigs of Dasymaschalon sootepense led to the isolation of a new 7-hydroxy aporphine alkaloid, 6a,7-dehydrodasymachaline (1) along with the five known compounds

Aristololactam alkaloids from the roots of Dasymaschalon rostratum.

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A novel aristololactam alkaloid, dasymalactam A (1), together with nine known analogues (2-10), were isolated from the roots of Dasymaschalon rostratum. Their structures were elucidated by IR, NMR and MS spectrums and comparisons with data reported in the literature. All

Cytotoxic alkaloids from stems, leaves and twigs of Dasymaschalon blumei.

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Bioassay-guided fractionation of the cytotoxic ethyl acetate extract from the stems of Dasymaschalon blumei (Annonaceae) led to the isolation of four aristololactam alkaloids, including the hitherto unknown 3,5-dihydroxy-2,4-dimethoxyaristolactam (1), as well as the three known compounds,

[A-ring formylated flavonoids and oxoaporphinoid alkaloid from Dasymaschalon rostratum Merr. et Chun].

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OBJECTIVE To study the chemical components in the stem of Dasymaschalon rostratum. METHODS The components were extracted with solvent, separated and purified with chromatographic methods, identified by NMR, MS, UV, IR and physicol-chemical constants. RESULTS Three A-ring-formylated flavonoids and

Polyoxygenated cyclohexene derivatives isolated from Dasymaschalon sootepense and their biological activities.

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Six new naturally occurring polyoxygenated cyclohexene derivatives together with eight related known derivatives, two known alkaloids, and two known flavonoid derivatives were isolated from bioassay-guided fractionation of the ethyl acetate extract of the leaves and twigs of Dasymaschalon

Dasymaschalolactams A-E, Aristolactams from a Twig Extract of Dasymaschalon dasymaschalum.

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Five new aristolactam alkaloids (1-5), dasymaschalolactams A-E, and the first isolation of dasymaschalolactone (17) as a natural product, together with 19 known compounds (6-16 and 18-25) were isolated from the twig extract of Dasymaschalon
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