dermatofibrosarcoma/phosphatase

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Dermatofibrosarcoma protuberans and its tissue culture study -- ultrastructural, enzyme histochemical and immunological study.

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Dermatofibrosarcoma protuberans arizing in the thigh of a 23-year-old female is reported with an investigation of tumor cell character by electron microscopy, enzyme histochemistry, immunological and in vitro tissue culture techniques. The tumor tissue showed histologically a peculiar storiform

Dermatofibrosarcoma Protuberans in a Patient With Cowden Syndrome: Revisiting the PTEN and PDGF Pathways.

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PTEN hamartoma tumor syndrome, of which Cowden syndrome (CS) is the most recognized variant, is characterized by multiple benign and malignant tumors of ectodermal, mesodermal, and endodermal origins, secondary to germline mutation in the phosphatase and tensin homolog (PTEN) gene.

Establishment of a human dermatofibrosarcoma protuberans cell line: cytological characteristics.

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We established a dermatofibrosarcoma protuberans (DFSP) cell line derived from a DFSP tumor from a 69-year-old female. The population doubling time of the cells was about 45 hours. The cells were mostly round, although a few triangular or spindle-shaped cells were also found. They could not be

Expression of the human progenitor cell antigen CD34 (HPCA-1) distinguishes dermatofibrosarcoma protuberans from fibrous histiocytoma in formalin-fixed, paraffin-embedded tissue.

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BACKGROUND Histologic distinction of dermatofibrosarcoma protuberans (DFSP) from fibrous histiocytoma (FH) may be difficult. In addition, differential diagnosis is hampered by the lack of appropriate immunohistochemical markers that reliably distinguish between these two entities. OBJECTIVE This

Specificity and sensitivity of differentiation antigens in superficial soft tissue tumors: comparison of SMA, calponin, H-caldesmon, C-kit, PLAP and HPL.

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We examined the expression pattern of smooth muscle actin (SMA), h-caldesmon (HCD), calponin (CALP), placental alkaline phosphatase (PLAP) and human placental lactogen (HPL) in benign and malignant spindle cell superficial soft tissue tumors in order to determine the role of these markers in

Enzyme histochemical observation of fibrohistiocytic tumors.

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The reactivity of lysosomal enzymes in 17 fibrohistiocytic tumors were examined histochemically to evaluate the histiocytic nature of the tumors. The lysosomal enzymes examined were acid phosphatase (Ac-P), non-specific esterase (NS-E), beta-glucuronidase (beta-GL), and N-acetyl-beta-glucosaminidase

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