di 2 ethylhexyl phthalate/atrofiere

Linkul este salvat în clipboard

ArticoleStudii cliniceBrevete

Alegeți tipul de sortare

Pagină 1 din 73 rezultate

Subchronic toxicity of Di(2-ethylhexyl)phthalate in common marmosets: lack of hepatic peroxisome proliferation, testicular atrophy, or pancreatic acinar cell hyperplasia.

Numai utilizatorii înregistrați pot traduce articole

To evaluate the toxicological effect, di(2-ethylhexyl)phthalate (DEHP) was administered orally at 100, 500, and 2500 mg/kg to four male and four female marmosets in each group for 13 weeks. Its potentials of hepatic peroxisome proliferation, testicular atrophy, and pancreatic acinar cell hyperplasia

Alterations of activities of cytosolic phospholipase A2 and arachidonic acid-metabolizing enzymes in di-(2-ethylhexyl)phthalate-induced testicular atrophy.

Numai utilizatorii înregistrați pot traduce articole

Di-(2-ethylhexyl) phthalate (DEHP), a peroxisome proliferator-activated receptor alpha (PPARalpha) ligand, alters the lipid composition of rat testis, yet the mechanism is unclear. In this study, we investigated the effect of DEHP on the synthesis and metabolism of arachidonic acid (AA), a precursor

Prevention of di(2-ethylhexyl)phthalate-induced testicular atrophy in rats by co-administration of the vitamin B12 derivative adenosylcobalamin.

Numai utilizatorii înregistrați pot traduce articole

The administration of 2g/kg of di(2-ethylhexyl)-phthalate (DEHP)-induced severe testicular atrophy coincident with the reduction of testicular specific lactate dehydrogenase (LDH-X) activity, zinc, magnesium, and potassium concentrations in rats. Co-administration of DEHP and adenosyl cobalamin

Testicular atrophy induced by di-2-ethylhexyl phthalate: effect of zinc supplement.

Numai utilizatorii înregistrați pot traduce articole

The administration of di-2-ethylhexyl phthalate (DEHP) to young male rats was found to cause testicular atrophy and loss of testicular zinc. In an attempt to test the hypothesis that a cause and effect relationship exists between DEHP-induced loss of testicular zinc and testicular injury, zinc was

Testicular atrophy of rats induced by di-2-ethylhexyl phthalate: effects of vitamin A and zinc concentrations in the testis, liver and serum.

Numai utilizatorii înregistrați pot traduce articole

Dietary administration of di-2-ethylhexyl phthalate (DEHP, 2% in diet) for 1 week to young male Wistar rats was found to cause testicular atrophy. Zinc (Zn) concentration in the testis and liver of DEHP-treated rats was lower than that in controls. Vitamin A concentration in serum and testis was

Mono-2-ethylhexyl phthalate, a metabolite of di-(2-ethylhexyl) phthalate, causally linked to testicular atrophy in rats.

Numai utilizatorii înregistrați pot traduce articole

Acute testicular atrophy results when appropriate dosages of di-(2-ethylhexyl) phthalate (DEHP) or its hydrolysis product mono-2-ethylhexyl phthalate (MEHP) are given to male rats. Events thought to be involved in this pathological effect also occur in cultures of testicular cells in vitro, but

Testicular atrophy induced by di(2-ethylhexyl)phthalate: changes in histology, cell specific enzyme activities and zinc concentrations in rat testis.

Numai utilizatorii înregistrați pot traduce articole

Daily administration of 2g/kg/day di(2-ethylhexyl)phthalate (DEHP) to immature rats was found to cause testicular atrophy and reduce zinc concentration. Specific activities of testicular enzymes associated with postmeiotic spermatogenic cells, such as lactate dehydrogenase isozyme-X, hyaluronidase

Strain differences in susceptibility to di-2-ethylhexyl phthalate-induced testicular atrophy in mice.

Numai utilizatorii înregistrați pot traduce articole

It is well known that the oral administration of di-2-ethylhexyl phthalate (DEHP) produces severe seminiferous tubular atrophy in rats, but mice are far less sensitive. In the present experiment, we demonstrated that one strain of mice derived from ICR mice, Crj:CD-1, was very sensitive to

Influence of dietary zinc on di(2-ethylhexyl)phthalate-induced testicular atrophy and zinc depletion in adult rats.

Numai utilizatorii înregistrați pot traduce articole

Groups of 48 adult male F344 rats were maintained on synthetic diets containing 20 ppm (normal), 2 ppm (low), or 200 ppm (high) zinc. After 1 week of acclimation to the various diets, groups of 12 rats from each dietary regimen were gavaged for 13 consecutive days with 0.0 (vehicle), 0.33, 1.0, or

Reversibility of testicular atrophy induced by Di(2-ethylhexyl) phthalate in rats.

Numai utilizatorii înregistrați pot traduce articole

Previous studies have shown that di(2-ethylhexyl) phthalate (DEHP) results in atrophy of testes and accessory sex organs accompanied by a decreased testicular concentration of zinc in rats. An experiment was performed to determine whether those changes in rat testes are reversible changes. Young

Effect of testosterone on the testicular atrophy caused by di(2-ethylhexyl)phthalate (DEHP).

Numai utilizatorii înregistrați pot traduce articole

The involvement of testosterone in di(2-ethylhexyl)phthalate (DEHP) induced testicular injury has been examined by coadministration of testosterone (1 mg/kg) along with DEHP (2000 mg/kg) daily for 15 days. The coadministration of testosterone and DEHP appears to have prevented the testicular injury

Melatonin alleviates meiotic defects in fetal mouse oocytes induced by Di (2-ethylhexyl) phthalate in vitro.

Numai utilizatorii înregistrați pot traduce articole

Di (2-ethylhexyl) phthalate (DEHP), an estrogen-like compound that is a ubiquitous environmental contaminant, has been reported to adversely affect human and mammalian reproduction. Many studies have found that exposure to DEHP during pregnancy perturbs female germ cell meiosis and is detrimental to

The effect of the plasticizer di-2-ethylhexyl phthalate on the survival of stored RBCs.

Numai utilizatorii înregistrați pot traduce articole

Recent in vitro studies have shown that di-2-ethylhexyl-phthalate (DEHP) inhibits the deterioration of RBCs during refrigerated storage in containers that use this compound as a plasticizer. The experiments described in this report were designed to assess whether this in vitro protective effect of

Gene expression analysis of the rat testis after treatment with di(2-ethylhexyl) phthalate using cDNA microarray and real-time RT-PCR.

Numai utilizatorii înregistrați pot traduce articole

To investigate the effects of di(2-ethylhexyl) phthalate (DEHP) on gene expression in rat testis, 6-week-old male Sprague-Dawley rats were given a single oral dose of 20 or 2000 mg/kg and euthanized 3, 6, 24, or 72 h thereafter. Terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling

Testicular atrophy produced by phthalate esters.

Numai utilizatorii înregistrați pot traduce articole

In a 90-day toxicity study in rats, di-(2-ethylhexyl)phthalate (DEHP) produced testicular atrophy. To characterise further the testicular toxicity of phthalate esters the effect of age on the induction of testicular atrophy has been examined as well as the reversibility of the lesions and the

Anterior
1
2
3
4
5
Următor →

Alăturați-vă paginii
noastre de facebook

Herbal & Natural Medicine

Cea mai completă bază de date cu plante medicinale susținută de știință

Funcționează în 55 de limbi
Cure pe bază de plante susținute de știință
Recunoașterea ierburilor după imagine
Harta GPS interactivă - etichetați ierburile în locație (în curând)
Citiți publicațiile științifice legate de căutarea dvs.
Căutați plante medicinale după efectele lor
Organizați-vă interesele și rămâneți la curent cu noutățile de cercetare, studiile clinice și brevetele

Tastați un simptom sau o boală și citiți despre plante care ar putea ajuta, tastați o plantă și vedeți boli și simptome împotriva cărora este folosit.
* Toate informațiile se bazează pe cercetări științifice publicate