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estradiol 17 beta/necroză

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ArticoleStudii cliniceBrevete
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Female steroid hormones regulate production of pro-inflammatory molecules in uterine leukocytes.

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Estrogens and progesterone could be among the environmental signals that govern uterine immune cell synthesis of pro-inflammatory substances. In order to investigate this possibility, we first mapped expression of the inducible nitric oxide synthase (iNOS) and tumor necrosis factor-alpha (TNF-alpha)

Estrogens and cell death in murine uterine luminal epithelium.

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The luminal epithelium of adult ovariectomized mice responds to estradiol-17 beta with a synchronised wave of DNA synthesis and mitosis. Estriol, however, although producing a similar DNA-synthetic and mitotic response fails to cause an increase in cell number owing to a wave of cell death occurring

Efficacy and advantages in the use of low doses of Anandron and estrogen combination in the treatment of prostate cancer.

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Treatment effects of RU 23908 antiandrogen (Anandron) and estrogen in low doses on hormone-dependent rat prostatic adenocarcinoma (R3327-H) were investigated. Tumor-bearing Copenhagen rats were treated for 6 weeks with 8 micrograms Anandron and 1 microgram estradiol-17 beta every two days. Reduction

Effects of inhibin on rat gonadal differentiation and development in vitro.

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Previously we examined that inhibin-alpha subunit, transforming growth factor-beta 1 (TGF-beta 1) and epidermal growth factor (EGF) were expressed in sex-, cell- and stage-specific manners in perinatal rat gonads. To clarify effects of these growth factors on the rat gonadal differentiation and

Experimentally induced intravaginal Tritrichomonas foetus infection in the estrogenized mouse.

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Studies were initiated to establish and maintain intravaginal Tritrichomonas foetus infections in female BALB/c mice as a model for elucidation of parasite and host factors that affect the course of vaginal protozoan infections. Results of these studies indicated that T. foetus infections could only

Pathogenesis of blood-filled cavities in estrogen-induced anterior pituitary tumors in male Sprague-Dawley rats.

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The formation of blood-filled cavities in developing tumors of the anterior pituitary of estrogen-treated male Sprague-Dawley rats was studied in a serial sacrifice experiment. Two treated and 2 control rats were killed at each of 15 time points ranging from 7-272 days after sc implantation of an

Combining two independent indirect methods as a new possibility for screening the illegal use of growth promotants.

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In this study the possibilities of combined indirect screening methods for the growth promotants clenbuterol and estradiol-17 beta benzoate and the combination of both these agents were investigated. Three groups of 5 male goat kids (two months of age) were treated for 4 weeks; clenbuterol per os,

Estrous stage determination in rats by means of scanning electron microscopic images of uterine surface epithelium.

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With the results presented in this paper we devised an alternative method to precisely date the rat endometrium in relation to the estrous cycle. This is done by the exclusive use of scanning electron microscopy. Owing to its short estrous cycle (4 to 6 days, depending on age), the rat is ideally
17-beta estradiol (17-beta E(2)) attenuates the expression of vascular cell adhesion molecule 1 (VCAM-1) in vivo at physiological levels (pg/ml), whereas supraphysiological concentrations of 17-beta E(2) (ng/ml) are required in vitro. We assessed whether a metabolite of estrogen, which could only be
The effect of 17 beta-estradiol on interleukin-6 (IL-6) synthesis was examined in murine bone marrow-derived stromal cell lines, normal human bone-derived cells, and nontransformed osteoblast cell lines from mice and rats. In all these cell types IL-6 production was stimulated as much as 10,000-fold
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