fetal distress/hypoxia

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The transcription factor c-Myc suppresses MiR-23b and MiR-27b transcription during fetal distress and increases the sensitivity of neurons to hypoxia-induced apoptosis.

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Previous studies reported that the expression of miR-23b-27b cluster was downregulated in embryonic brain cortices during hypoxia-induced neuronal apoptosis. However, the mechanism underlying this downregulation is not completely understood. Here, we report that the transcription factor c-Myc plays

Lawrence D. Longo: from chronic fetal hypoxia to proteomic predictors of fetal distress syndrome - a life devoted to research and mentoring based on virtue-ethics.

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The present chapter presents the experience of the author during his fellowship granted by the Fogarty Foundation of the NIH in the Division of Perinatal Biology, Loma Linda University, from 1989 to 1991. Experiments on maternal and fetal responses to long-term hypoxemia (including high-altitude)

Hypoxia of the fetus and newborn infant. Acute and chronic fetal distress.

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[Anoxia and acidosis in the evaluation of fetal distress during labor].

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[Approximate entropy analysis of fetal heart rate variability and its application in the diagnosis of fetal distress].

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To introduce approximate entropy (ApEn) in the analysis of fetal heart rate variability (FHRV) and to discuss the relationship between the ApEn values and perinatal outcomes, 67 computerized cardiotocographs were recorded. Approximate entropy and index in time domain were used to analyze FHRV. After

Determination of pH or lactate in fetal scalp blood in management of intrapartum fetal distress: randomised controlled multicentre trial.

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OBJECTIVE To examine the effectiveness of pH analysis of fetal scalp blood compared with lactate analysis in identifying hypoxia in labour to prevent acidaemia at birth. METHODS Randomised controlled multicentre trial. METHODS Labour wards. METHODS Women with a singleton pregnancy, cephalic

[Diagnostic value of cardiac monitoring in women with threatened fetal distress].

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Use of cardiotocography as the fetal status index in complex with other criteria and medical algorithms in pregnant women during the IIIrd trimester helped better select the term and method of delivery for each patient with threatened fetal distress. The choice of the optimal individual method of

Justification of caesarean section for fetal distress.

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A study was done from May 1995 to February 1996 to evaluate the justification of caesareans for fetal distress by examining the circumstances leading to operative delivery for compromised fetus. Of the 1096 caesareans, 179 (16.33%) were for fetal distress. One hundred and seven (59.78%) were

[Blood gas and acid-base equilibrium in normal pregnancy and pregnancy with fetal distress by vaginal delivery or cesarean section].

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Blood gas and acid-base assessment of maternal dorsalis pedis artery and umbilical artery and vein was carried out immediately after delivery in 46 cases of normal term pregnancy and 41 cases of pregnancy with fetal distress (FD). Blood gas and acid-base equilibrium differences between vaginal

Oligohydramnios: antepartum fetal urine production and intrapartum fetal distress.

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Animal and human studies suggest that fetal oliguria is a normal physiologic response to hypoxemia. To assess the clinical significance of this observation, we studied (before their admission) 51 fetuses of women whose pregnancies were complicated by oligohydramnios at greater than or equal to 38

Haemodynamic changes in IUGR fetus with chronic hypoxia evaluated by fetal heart-rate monitoring and Doppler measurement of blood flow velocity.

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The measurement of fetal blood flow velocity and 24 h monitoring of fetal heart-rate (FHR) using a computer were performed to clarify the haemodynamics of growth-retarded fetuses with chronic hypoxia. One hundred normal-growth and 18 growth-retarded fetuses were analysed. All the growth-retarded

Fetal size and growth velocity in the prediction of intrapartum caesarean section for fetal distress.

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OBJECTIVE To evaluate and compare third trimester ultrasound measurements of fetal size and growth velocity in the prediction of intrapartum operative delivery for fetal distress and admission to the special care baby unit in a low risk antenatal population undergoing labour at

Acute physiopathological and histopathological effects of fetal distress on the fetal stomach: an experimental study.

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Although effects of stress on the stomach have been extensively investigated in children and adults, our knowledge about effects of fetal distress (FD) on the fetal stomach is quite limited. Therefore, an experimental study was planned to evaluate the effects of FD on fetal gastric physiology and

Spinal motor neuron excitability in newborns following fetal distress: sub-clinical depression revealed by soleus H-reflex.

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OBJECTIVE To explore possible spinal cord dysfunction in clinically unaffected newborns emerging from fetal distress, using H-Reflex. METHODS This cross-sectional study comprised 48 full-term newborn infants investigated between 8h and 10 days after birth. Twenty-one (21) had fetal distress defined

Is intrapartum fetal blood sampling a gold standard diagnostic tool for fetal distress?

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Developed in 1960s, cardiotocography is a screening test and fetal blood sampling (FBS) is an adjunctive, diagnostic technique to detect fetal hypoxia. A fetal blood sample pH value of less than 7.20 has a higher specificity than a pathological CTG to predict low Apgar score at 1 min. Though with a

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