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glycyrrhetinic acid/hemoragie
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6 rezultate
Effect of 18β-glycyrrhetinic acid on cerebral vasospasm caused by asymmetric dimethylarginine after experimental subarachnoid hemorrhage in rats.
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OBJECTIVE
Cerebral vasospasm (CVS) after subarachnoid hemorrhage (SAH) is characterized by the severe constriction of an artery, which often leads to unfavorable outcomes. CVS after SAH is closely associated with asymmetric dimethylarginine (ADMA) and connexin. The effect of 18β-glycyrrhetinic acid
[Pseudohyperaldosteronism secondary to licorice poisoning associated with hemorrhagic gastritis].
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The case is described of a 6 1/2-year-old child with pseudohyperaldosteronism due to excessive and prolonged liquorice ingestion. The authors debate its differential diagnosis, its physiopathological mechanism (glycyrrhetinic acid, the active metabolite of liquorice, inhibits the conversion of
[Role of arterial myo-endothelial gap junction on the vascular contractile reactivity following hemorrhagic shock in rats].
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OBJECTIVE
To observe the role of arterial myo-endothelial gap junction (MEGJ) on endothelium-dependent and independent vascular contractile reactivity following hemorrhagic shock in rats.
METHODS
Fifty-six SD rats were randomly divided into noradrenaline (NE) group and myricetin group. NE group was
Discovery of glycyrrhetinic acid as an orally active, direct inhibitor of blood coagulation factor xa.
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BACKGROUND
Factor Xa (FXa) plays an important role in blood coagulation. This study investigated glycyrrhetinic acid, a small molecule derived from Chinese herbs, and whether it has a direct inhibitory effect on FXa to display its anticoagulant activity.
METHODS
Enzyme activities of FXa, plasmin,
Licorice Root Associated With Intracranial Hemorrhagic Stroke and Cerebral Microbleeds.
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Chinese Licorice root "gan zao" (Glycyrrhiza uralensis) is an ancient, medicinal herb utilized in Traditional Chinese Medicine for its presumably antiulcer, anti-inflammatory, antiviral, antibacterial, and expectorant properties. One of the major biologically active components is
Gap junction blockade induces apoptosis in human endometrial stromal cells.
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One of the most dynamic adult human tissues is the endometrium. Through coordinated, cyclical proliferation, differentiation, leukocyte recruitment, apoptosis, and desquamation, the uterine lining is expanded and shed monthly, unless pregnancy is established. Errors in these steps potentially cause
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