gongronema/antidiabetic

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Evaluation of the properties of Gongronema latifolium in phospholipon 90H based solid lipid microparticles (SLMs): an antidiabetic study.

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BACKGROUND Gongronema latifolium Benth Hook, (Asclepiadaceae) is a tropical rainforest plant primarily used in traditional folk medicine in the treatment of malaria, diabetes, hypertension, and as laxative. OBJECTIVE To study the antidiabetic properties of Gongronema latifolium-loaded solid lipid

Antihyperglycemic effect of aqueous and ethanolic extracts of Gongronema latifolium leaves on glucose and glycogen metabolism in livers of normal and streptozotocin-induced diabetic rats.

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The present study was designed to investigate the antihyperglycemic effects of aqueous and ethanolic extracts from Gongronema latifolium leaves on glucose and glycogen metabolism in livers of non-diabetic and streptozotocin-induced diabetic rats. To investigate the effects of aqueous or ethanolic

Anti-lipid peroxidative activity of Gongronema latifolium in streptozotocin-induced diabetic rats.

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This study was designed to investigate the anti-lipid peroxidative effects of aqueous extracts from Gongronema latifolium (Utazi) leaves in non-diabetic and streptozotocin-induced diabetic rats. We evaluated plasma lipid peroxidation product (malondialdehyde, MDA) and antioxidant enzyme, superoxide

Effect of Gongronema latifolium ethanol leaf extract on gastric acid secretion and cytoprotection in streptozotocin-induced diabetic rats.

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OBJECTIVE Gongronema latifolium leaves have been used in folklore medicine to manage diabetes mellitus and alleviate dyspepsia. This study aimed to provide a pharmacological basis to the medicinal use ofGongronema latifolium as an antidiabetic and antiulcerogenic agent in diabetes

Antihyperglycaemia and related gene expressions of aqueous extract of Gongronema latifolium leaf in alloxan-induced diabetic rats.

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Context:Gongronema latifolium Benth (Asclepiadaceae) has been highly utilized in controlling diabetes mellitus traditionally in the eastern part of Nigeria. Objectives: Antihyperglycaemic and related gene expressions of aqueous extract of Gongronema latifolium leaf in

Gongronema latifolium leaf extract modulates hyperglycaemia, inhibits redox imbalance and inflammation in alloxan-induced diabetic nephropathy

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Background: Gongronema latifolium leaf is used traditionally to treat diabetes and other diseases. The present study aimed to provide the modulatory effect of G. latifolium on hyperglycemia, inhibitory effect of redox

A Soxhlet Extract of Gongronema latifolium Retains Moderate Blood Glucose Lowering Effect and Produces Structural Recovery in the Pancreas of STZ-Induced Diabetic Rats.

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BACKGROUND Gongronema latifolium Benth. (GL) possesses considerable glucose lowering effects able to be utilized on a large-scale. This paper investigates the effects of a Soxhlet extract on hyperglycemia, Langerhans islets and glucose uptake by abdominal muscles. METHODS Ethanol and a Soxhlet

Evaluation of ethnomedical claim III: anti-hyperglycemic activities of Gongronema latifolium root and stem.

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BACKGROUND The insulinotropic activity of the combined root and stem of Gongronema latifolium (Asclepiadaceae) was evaluated to justify its African ethnomedicinal use in the management of diabetes. METHODS A methanolic extract and its chromatographic fractions (A1 -A6 ) were tested for

Evaluation of methanol extract of Gongronema latifolium leaves singly and in combination with glibenclamide for anti-hyperglycemic effects in alloxan-induced hyperglycemic rats.

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OBJECTIVE This study evaluated the anti-hyperglycemic effect of the methanol extract of Gongronema latifolium leaves singly and in combination with an oral hypoglycemic agent; glibenclamide. METHODS The plant material was extracted with methanol for 48 h using cold maceration and concentrated in

Gongronema latifolium Benth. leaf extract attenuates diabetes induced neuropathy via inhibition of cognitive, oxidative stress and inflammatory response.

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Gongronema latifolium (G. latifolium) Benth. leaf is traditionally used to treat diabetes mellitus (DM) and other diseases in Nigeria and West Africa. This study was performed to evaluate the neuroprotective effect of aqueous extract of G. latifolium leaf against DM by enhancing

Comparative hypoglycemic potentials and phytochemical profiles of 12 common leafy culinary vegetables consumed in Nsukka, Southeastern Nigeria.

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Background Metabolic disease like diabetes mellitus is on the increase in developing countries due to lack of access to orthodox medicine owing to its high cost. Health benefits of culinary vegetables cannot be overemphasized. This study therefore aims to profile the hypoglycaemic potentials of 12

Antioxidant effects of Gongronema latifolium in hepatocytes of rat models of non-insulin dependent diabetes mellitus.

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Gongronema latifolium is a rainforest plant, which has been traditionally used in the South Eastern part of Nigeria for the management of diabetes. The effects of oral administration of aqueous and ethanolic G. latifolium leaf extracts for 2 weeks on streptozotocin-induced diabetic rats were

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