The test involves chewing a chewing gum for 4 minutes plus a standard Horton disease diagnostic

The test involves chewing a chewing gum for 4 minutes

Horton Disease

chewing gum

CHU Limoges

Chewing Gum Test for the Diagnosis of Giant Cell Arteritis (Horton's Disease) - ChewingHort

Evaluation of Sensitivity, Specificity, Positive and Negative Predictive Values of the Chewing Gum Test for the Diagnosis of Giant Cell Arteritis (Horton's Disease) - ChewingHort

Determination of:
True positive: Sick people correctly identified as sick False positive: Healthy people incorrectly identified as sick True negative: Healthy people correctly identified as healthy False negative: Sick people incorrectly identified as healthy
Then wa calculate:
the number true positives TP the number of false positives FP the number of true negatives TN the number of false negatives.FN
Specificty= TN/(TN+FP) Sensitivity= : TP/(TP+FN) The test is performed twice an hour apart, to verify its reproducibility, before the introduction of corticosteroid therapy, with chewing gums without sugar.

University Hospital, Limoges

50 control patients : blood from French national blood service (EFS)

Giant Cells Arteritis

Clinical evaluation

Paraclinical evaluation

Thoraco-abdominal scanner injected or PET scanner if contraindication for scanner.

Imaging

Ophthalmologic examination

Dosage of biomarkers

UniversityHospitalGrenoble

Biomarkers in Giant Cells Arteritis

For dosage of biomarkers in serum, like serum amyloid A or interleukins.

hyperesthesia/cefalee

Chewing Gum Test for the Diagnosis of Giant Cell Arteritis (Horton's Disease) - ChewingHort

Biomarkers in Giant Cells Arteritis

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