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Uterine Sarcoma: The Indian Scenario.

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Uterine sarcomas are rare, highly malignant tumours comprising < 1 % of all gynaecologic malignancies. To evaluate clinical presentation, histolopathologic pattern and outcome of uterine sarcomas presenting to a tertiary referral centre over an 8 year period (2004-2012). All histologically proven

Transformation of Indian muntjac cells by murine and avian sarcoma viruses.

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Indian muntjac cells were efficiently transformed by murine sarcoma virus (MSV) and avian sarcoma viruses (ASV). When colony formation of the infected cells was examined in soft agar, many colonies were formed by the ASV-injected cells but no colony was seen in the MSV-infected cells. The

Double transformation of Indian muntjac cells by avian and murine sarcoma viruses.

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Avian sarcoma virus-transformed Indian muntjac cells, SR-Mm-1, formed foci by murine sarcoma-xenotropic murine leukemia virus complex [MSV(X-MuLV)] superinfection. The response of SR-Mm-1 and parental normal Indian muntjac Mm-2K cells to MSV(X-MuLV) infection was compared. Focus formation by

Limb sparing surgery in soft tissue sarcoma of extremities: an Indian perspective.

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This is a retrospective study of 57 patients with extremity soft tissue sarcomas treated at Gujarat Cancer Research Institute, Gujarat, India from January 2005 to December 2007. It aims to review the feasibility of limb sparing surgery for extremity soft tissue sarcoma in Indian population.

Prognostic Factors in Indian Patients Operated for Soft Tissue Sarcomas-a Retrospective Cross-sectional Analysis.

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Soft tissue sarcomas are a rare entity. While surgery is established as the mainstay of treatment, the exact role and sequencing of adjuvant therapy is not well defined. Literature on Indian patients with soft tissue sarcoma with respect to clinical profile and prognostic factors is scarce. We

Oral Cavity Cancer in the Indian Subcontinent - Challenges and Opportunities.

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Oral cavity cancer (OCC) poses a global challenge that plagues both the Orient and the Occident, accounting for an estimated 350 000 new cases and 177 000 deaths in 2018. OCC is a major public health problem in the Indian subcontinent, where it ranks among the top three cancer types in both

Multiple primary cancers in Indian population: metachronous and synchronous lesions.

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A retrospective study of 177 patients attending Tata Memorial Hospital over a period of 40 years from 1942 through 1981 is presented. These patients who had "primary lesions" in the head and neck region, breast, esophagus, lung, and elsewhere as carcinoma or sarcoma developed "second primary" at

AIDS-associated kaposis-sarcoma in tanzanians of Indian origin - report of cases and review of literature.

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Kaposi's sarcoma (KS) was up to the 1980's seen as a rare indolent sporadic disease in Southern Europe and as an endemic disease in East and Central Africa. With the onset of the HIV/AIDS epidemic a more aggressive, disseminated type of KS was recognized in HIV infected people with AIDS.

[The chromosome variability of the Indian muntjac in somatic cell hybrids].

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Hybrids were produced between the Indian muntjak fibroblasts and rat Jensen sarcoma cell line (JF1) auxotrophic for asparagine. They were selected without cloning under conditions providing survival of parental Indian muntjak and hybrid cells. This allowed to compare the Indian muntjak chromosome

Disseminated Kaposi's sarcoma as a presenting sign of HIV in an Indian male: A case report with dermoscopic findings

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Kaposi's sarcoma (KS) is one of the AIDS-defining illnesses, which tends to occur at low CD4 count. It is the most common malignancy associated with HIV disease. Yet, there is a paucity of Indian case reports of KS in the English literature. We report the case of a 45-year-old HIV-positive

Cytolytic activity of cytotoxin isolated from Indian cobra venom against experimental tumor cells.

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Cytolytic activity of cytotoxin isolated from the venom of the Indian cobra (Naja naja) on experimental tumor cells was far stronger than that on normal cells such as peritoneal exudate cells, spleen cells, and erythrocytes of the rat. The effect on Yoshida sarcoma cells was temperature-dependent,

Venom of Indian monocellate cobra and Russell's viper show anticancer activity in experimental models.

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Indian monocellate cobra (Naja kaouthia) and Russell's viper (Vipera russelli) are common snakes of the East Indian sub-peninsula. The anticarcinogenic activities of their crude venoms were studied on carcinoma, sarcoma and leukemia models. Sub-lethal doses of venoms showed cytotoxicity on Ehrlich

Amino acid sequence of cytotoxin IIa isolated from the venom of the Indian cobra (Naja naja).

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A cytotoxic basic polypeptide, designated as cytotoxin IIa, was purified to homogeneous state from the venom of the Indian cobra (Naja naja) by a combination of gel filtration on Sephadex G-50, CM-cellulose chromatography, and fast protein liquid chromatography. Cytotoxin IIa is a single polypeptide

Low levels of p53 mutations in Indian patients with osteosarcoma and the correlation with fluoride levels in bone.

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The pathogenesis of osteogenic sarcoma is not known. Recently, chronic fluoride exposure has been incriminated as having a possible etiologic role by causing a nonspecific osteoblast proliferation. We were interested in exploring the possible relationship between fluoride bone content and p53

(-)-Epigallocatechin-3-gallate induces apoptosis and suppresses proliferation by inhibiting the human Indian Hedgehog pathway in human chondrosarcoma cells.

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OBJECTIVE Chondrosarcoma is a soft tissue sarcoma with a poor prognosis that is unresponsive to conventional chemotherapy. The regulatory mechanisms for the rapid proliferation of chondrosarcoma cells and the particular aggressiveness of this sarcoma remain poorly understood. In this study, we

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