keratoconjunctivitis/albumină

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Human albumin eye drops as a therapeutic option for the management of keratoconjunctivitis sicca secondary to chronic graft-versus-host disease after stem-cell allografting.

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BACKGROUND Keratoconjunctivitis sicca from chronic graft-versus-host disease (cgvhd) after allogeneic stem cell transplantation is common, leading to severe corneal damage and blindness if not treated. We retrospectively examined the efficacy and safety of pooled human albumin eye drops (haeds) for

Identification of human tear fluid biomarkers in vernal keratoconjunctivitis using iTRAQ quantitative proteomics.

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BACKGROUND Understanding and treating vernal keratoconjunctivitis (VKC) has been a challenge because the pathogenesis is unclear and antiallergic therapy often unsuccessful. The aim of the study was to analyze peptide profiles in human tears using mass spectrometry to elucidate compositional

The value of exogenous interferon in adenovirus keratoconjunctivitis. Preliminary results.

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Fourteen patients with confirmed adenovirus (kerato-) conjunctivitis were treated at random with either exogenous interferon alpha (Le) (3 x 10(6) IU/ml, 1 drop daily) or with albumin. We observed no clinically relevant therapeutic effects. However, interferon seemed to exert a prophylactic effect

Vernal keratoconjunctivitis: the significance of immunoglobulin E levels in tears and serum.

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Vernal keratoconjunctivitis (VC) is an inflammatory disorder of the outer eye, probably of allergic etiology. The present study was performed on patients with a typical clinical appearance of VC and examined periodically for serum and tear IgE and albumin (HSA). The geometric mean of serum and tear

Use of human fibroblast-derived (beta) interferon in the treatment of epidemic adenovirus keratoconjunctivitis.

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Topical application of human fibroblast-derived (beta) interferon (HulFN-beta) has been used in treatment of epidemic keratoconjunctivitis due to adenovirus. Patients received a total of 1-2 x 10(5) reference units of HulFN-beta per day, divided into 8-10 drops. Control patients received

[Keratoconjunctivitis sicca in Sjögren's syndrome: diagnostic significance of relative protein composition of tears].

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Six protein components were detected in the tears by exclusive high-pressure liquid chromatography. By their molecular weight, these components were identified as lacrimal prealbumin, human serum albumin, lactoferin, IgG, and IgA. The relative content of these proteins in tears correlates with the

Design, synthesis, and evaluation of N-acyl modified sialic acids as inhibitors of adenoviruses causing epidemic keratoconjunctivitis.

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The adenovirus serotype Ad37 binds to and infects human corneal epithelial (HCE) cells through attachment to cellular glycoproteins carrying terminal sialic acids. By use of the crystallographic structure of the sialic acid-interacting domain of the Ad37 fiber protein in complex with sialyllactose,

Common features of atopic dermatitis with hypoproteinemia.

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OBJECTIVE The purpose of this study was to identify the causes, symptoms, and complications of hypoproteinemia to prevent hypoproteinemia and provide appropriate treatment to children with atopic dermatitis. METHODS Children diagnosed with atopic dermatitis with hypoproteinemia and/or

Measurement of total IgE antibody levels in lacrimal fluid of patients suffering from atopic and non-atopic eye disorders. Evidence for local IgE production in atopic eye disorders?

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Total IgE levels in lacrimal fluid of patients suffering from different eye disorders were quantitatively measured by a modification of the paper radio immuno sorbent test (PRIST). The geometric mean values for patients with atopic conjunctivitis, patients with keratoconjunctivitis vernalis, and

Identification of hemopexin in tear film.

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Human tear fluid is a complex mixture of aqueous lipids, proteins, enzymes, and other biochemical and cellular elements. By conventional comparative proteomic approaches, we investigated the proteome in human tear fluid and compared the tear protein profile of normal control subjects with that of

Autologous serum eye drops for the treatment of dry eye diseases.

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Conventional treatment of dry eye mainly consists of the use of preservative-free artificial eye drops and punctal occlusion. None of the commercially available artificial tear preparations include essential tear components such as epidermal growth factor, hepatocyte growth factor, fibronectin,

Asymptomatic endemic Chlamydia pecorum infections reduce growth rates in calves by up to 48 percent.

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Intracellular Chlamydia (C.) bacteria cause in cattle some acute but rare diseases such as abortion, sporadic bovine encephalomyelitis, kerato-conjunctivitis, pneumonia, enteritis and polyarthritis. More frequent, essentially ubiquitous worldwide, are low-level, asymptomatic chlamydial infections in

An immunological study of papillary conjunctivitis due to contact lenses.

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Serum and tear levels of IgE were compared in patients with contact lens papillary conjunctivitis (CLPC), vernal keratoconjunctivitis (VC), healthy contact lens wearers (CLW), and healthy controls without lenses. The mean of serum IgE was elevated only in the VC group. Tear IgE levels were

Multivalent sialic acid conjugates inhibit adenovirus type 37 from binding to and infecting human corneal epithelial cells.

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Adenovirus type 37 is one of the main causative agents of epidemic keratoconjunctivitis. In a series of publications, we have reported that this virus uses sialic acid as a cellular receptor. Here we demonstrate in vitro that on a molar basis, multivalent sialic acid conjugated to human serum

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