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Exercise limitation is common in patients with chronic pulmonary venous hypertension. One postulated mechanism is ventilation-perfusion inequality secondary to vascular congestion and edema formation. To investigate this possibility, five patients with symptomatic, chronic mitral stenosis were
We present a case of a 21-year-old Caucasian woman at 27 weeks of pregnancy who was admitted to the obstetric department for pre-term labor. She received 10 mg of nifedipine 4 times in 1 h, according to the internal protocol. Shortly after, she brutally deteriorated with pulmonary edema and
Echocardiographic analysis of right ventricular ejection time (RVET), pre-ejection time (RVPEP), RVPEP/ET and isovolumic relaxation time (RVIRT) was performed in patients with acute or chronic right ventricular pressure overloading. Fifty-five patients undergoing right ventricular cardiac
BACKGROUND
Nodules of cells showing a striking histological similarity to those of arachnoid villi have previously been found closely adjacent to pulmonary venules in several diseases associated with alveolar hypoxia or pulmonary oedema including mitral stenosis, plexogenic pulmonary arteriopathy,
We have examined the effects of various interventions on protein degradation and synthesis in the in vitro left side perfused working rat heart preparation of Taegtmeyer, Hems and Krebs. In the absence of insulin, we could not detect any effects of increased pressure workload or of increased volume
Two patients with critical mitral stenosis underwent open mitral valvotomy during the third trimester of pregnancy. Fetal monitoring throughout heart-lung bypass produced evidence of acute fetal hypoxia. Healthy live full-term infants were subsequently delivered.
The following case report details an 88-year-old woman with severe mitral stenosis and moderate mitral regurgitation who presented with worsening dyspnea on exertion. The patient had undergone 4-vessel coronary artery bypass graft and mitral valve replacement 14 years before and was deemed high risk
OBJECTIVE
To analyze maternal and fetal outcome in pregnant undergone to cardiac surgery.
METHODS
We studied the evolution of 30 pregnant women submitted to cardiac surgery at the Hospital São Paulo, between Jan/81 and Dec/92 and, further, attended at this Hospital till the parturition. The
Changes in 2,3-DPG level have been studied in cardiosurgical patients. It has been shown that 2,3-DPG concentration increase, as a moderately fast mechanism in a common model of tissue pO2 regulation, is observed in almost half of patients with acquired heart valve defects. An increase in 2,3-DPG
The role of active and passive factors involved in the genesis of Pulmonary Arterial Hypertension (PAH) is analyzed in a group of eighty patients with several cardiopathies and pneumopathies. The group include: 20 patients with Chronic Obstructive Lung Disease (NODC), 20 with Diffuse intersticial
Pregnancy is a common decompensation factor for women with post-rheumatic mitral disease. However, valvular heart diseases causing severe acute respiratory distress are rare. Use of extracorporeal membrane oxygenation (ECMO) early in the event of cardiorespiratory failure after cardiac surgery may
Uncommon observation of endocardial fibroelastosis of the left auricle and ventricle found at autopsy. The 46-year-old female patient had her mitral valve replaced 15 months ago because of mitral stenosis (and slight incompetence). The left auricle with certainty did not show endocardial fibrosis at
Disorders of the heart frequently cause pulmonary dysfunction because of the close structural and functional association of the heart and lungs. The pulmonary vasculature is very commonly affected by cardiac pathology. The pulmonary vasculature is normally a low-pressure, low-resistance circuit with