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osteoradionecrosis/nicotine

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Risk assessment for osteoradionecrosis of the jaws in patients with head and neck cancer

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Objectives: To identify the potential risk factors for the occurrence of osteoradionecrosis (ORN) of the jaws among patients who have been treated with radiotherapy for head and neck malignancy. Methods: The study comprised of 231

Dental prevention of maxillo-mandibular osteoradionecrosis: A ten-year retrospective study

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Introduction: Osteoradionecrosis (ORN) remains a frequent complication of radiotherapy in head and neck cancer. As ORN management is often complex, it is essential to focus on its prevention, mainly by dental prophylaxis. The objectives

[Mandibular osteoradionecrosis: part I: severity factors].

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BACKGROUND The severe evolution for some patient presenting with osteoradionecrosis, even if classified in the same stages as other patients, suggests that there are aggravating factors. METHODS A retrospective study was made between 1992 and 2002 on all patient operated for mandibular

Osteoradionecrosis of the mandible.

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Osteoradionecrosis is a major complication of surgery or trauma in previously irradiated bone in the absence of tumor persistence. Radiation-induced vascular insufficiency rather than infection causes bone death. It occurs most commonly in the mandible after head and neck irradiation. Risk factors

[Teeth and irradiation: dental care and treatment of osteoradionecrosis after irradiation in head and neck cancer].

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Pre-irradiation dental care depends on teeth health, fields and dose of irradiation, compliance to fluorides, cessation of tobacco and psychosocial cofactors. Dental care aims at preventing complications and preserving the quality of life (eating, speech, and aesthetics). The role of hyperbaric

Predictive factors for osteoradionecrosis of the jaws: A retrospective study.

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BACKGROUND Osteoradionecrosis of the jaw (ORNJ) is a well-recognized complication of radiotherapy. The purpose of this study was to assess predictive factors for the development of ORNJ. METHODS A retrospective study of 325 patients with head and neck squamous cell carcinoma (HNSCC) treated at one

A study of factors contributing to the development of osteoradionecrosis of the jaws.

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The histories of 14 patients in whom osteoradionecrosis developed were compared with those of 28 patients who had similar tumors and/or treatment and were not afflicted with osteoradionecrosis. 1. Fourteen of 15 episodes of bone complications occurred in the mandible, and 70% occurred within 1 year

Osteoradionecrosis: an update.

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Osteoradionecrosis (ORN) of the mandible is the most serious and severe side effect of combined treatment of head and neck tumors. A new theory for the pathogenesis of ORN has been proposed relating it to a fibro-atrophic mechanism including free radical formation, endothelial dysfunction,

Osteoradionecrosis of the mandible after radiotherapy for head and neck cancer: risk factors and dose-volume correlations.

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Background: The project aimed at determining the incidence of mandibular osteoradionecrosis (ORN) after radiotherapy, possible risk factors, and mandibular dose-volume effects in a large cohort of head and neck cancer patients (HNC). Methods: The cohort consisted of 1224 HNC patients

Compliance with fluoride custom trays in irradiated head and neck cancer patients.

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OBJECTIVE The purpose of this study is to assess compliance with fluoride gel custom trays in irradiated head and neck cancer patients. METHODS One hundred fifty-five consecutive patients on remission following radiation therapy of head and neck cancers were assessed retrospectively for dental care

Evaluation of Clinical Outcomes of Osseointegrated Dental Implantation of Fibula Free Flaps for Mandibular Reconstruction.

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OBJECTIVE Dental implantation has been used for oral rehabilitation to improve cosmesis and function. OBJECTIVE We aim to evaluate the clinical outcomes and success rates of primary and secondary dental implant placement in vascularized fibula bone grafts used for segmental mandibulectomy

Complications of radiotherapy in laryngopharyngeal cancer: effects of a prospective smoking cessation program.

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BACKGROUND Radiotherapy (XRT) is effective as the primary treatment modality for laryngopharyngeal cancer; however, complications of XRT can result in significant morbidity. Few previous studies have examined the effect of continued smoking on complications of XRT. The authors of this report

[Dental state in patients with head and neck cancers].

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In France, in 2005, there were approximately 16,000 new cases of head and neck cancer. These cancers have an unfavourable prognosis: the survival rates at 3 and 10 years are 50% and 10% respectively. The consumption of alcohol and tobacco is the most important risk factor; in some countries HPV

[Teeth and irradiation in head and neck cancer].

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Pre-irradiation dental care depends on teeth health, fields and dose of irradiation, compliance to fluorides, cessation of tobacco and psychosocial cofactors. Dental care aims at preventing complications and preserving the quality of life (eating, speech and aesthetics). Approximately 11% of
Osteonecrosis of the jaw (ONJ) is a well-known side effect of bisphosphonate (BP) therapy. ONJ is specifically related to the intravenous form of BPs and is usually seen in combination with other risk factors, such as dental surgery, concurrent corticosteroids, chemotherapy, and tobacco use. The
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