palmitoleic/hepatită

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Palmitoleic acid reduces high fat diet-induced liver inflammation by promoting PPAR-γ-independent M2a polarization of myeloid cells

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Palmitoleic acid (POA, 16:1n-7) is a lipokine that has potential nutraceutical use to treat non-alcoholic fatty liver disease. We tested the effects of POA supplementation (daily oral gavage, 300 mg/Kg, 15 days) on murine liver inflammation induced by a high fat diet (HFD, 59% fat, 12 weeks). In

[Fatty acid composition of liver lipids in chronic hepatitis, liver cirrhosis and fatty liver].

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Fatty acid spectrum of liver tissue lipids was studied by means of gas-liquid chromatography in 58 bioptic samples from patients with chronic hepatitis, liver cirrhosis and fatty hepatosis. A statistically significant decrease in content of linoleic, arachidonic and docosahexaenic acids as well as

Fatty acid composition of serum lipids in bilharzial hepatic fibrosis and chronic active hepatitis.

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The fatty acid pattern of blood serum lipids was examined by gas liquid-chromatography in 30 cases with bilharzial hepatic fibrosis, 11 cases with chronic active hepatitis accompanied by jaundice, and 28 healthy individuals as a comparison group of the same socioeconomic class of patients. In

[Deviations in the level of serum lipids and higher fatty acids in liver cirrhosis and chronic hepatitis].

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Serum lipids and higher fatty acids were investigated in 141 patients with portal liver cirrhosis, 51 patients with chronic hepatitis and 40 clinically healthy subjects--controls. Lower contents of cholesterin in blood was found in the patients with liver cirrhosis as compared with the healthy as

A comparative study of serum lipid contents in pre and post IFN-alpha treated acute hepatitis C patients.

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BACKGROUND To study the effect of Interferon (INF) alpha-2b therapy on the serum lipids and fatty acid (FA) level in pre and post treated hepatitis C (HCV) patients. METHODS Fifty samples were collected from pre and post treated patients along with age and gender matched controls. After separating

Palmitoleic acid (n-7) attenuates the immunometabolic disturbances caused by a high-fat diet independently of PPARα.

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Palmitoleic acid (PMA) has anti-inflammatory and antidiabetic activities. Here we tested whether these effects of PMA on glucose homeostasis and liver inflammation, in mice fed with high-fat diet (HFD), are PPAR-α dependent. C57BL6 wild-type (WT) and PPAR-α-knockout (KO) mice fed with a standard

Pathogenesis of lipid metabolism disorder in hepatitis C: polyunsaturated fatty acids counteract lipid alterations induced by the core protein.

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OBJECTIVE Disturbance in lipid metabolism is one of the features of chronic hepatitis C, being a crucial determinant of the progression of liver fibrosis. Experimental studies have revealed that the core protein of hepatitis C virus (HCV) induces steatosis. METHODS The activities of fatty acid

Serum lipid profile as a marker of liver impairment in hepatitis B Cirrhosis patients.

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BACKGROUND Chronic HBV infection is a major cause of Cirrhosis and an important risk factor to develop hepatocellular carcinoma. The study is conducted to find out the changes in the lipid metabolism of HBV-cirrhosis patients. METHODS In the present study, serum lipid profiles of patients with

Fatty acid composition of lipoprotein lipids in hepatobiliary diseases.

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Liver damage and alterations in the exocrine function of the gland lead to a profound alteration of the plasma lipoprotein profile. To determine whether hepatic disease results in changes in the lipoprotein fatty acid composition, i.e. to determine whether liver function influences the homeostasis

Increased serum concentration of ceramides in obese children with nonalcoholic fatty liver disease.

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BACKGROUND Hepatic lipid accumulation is closely related to the development of insulin resistance, which is regarded as one of the most significant risk factors of nonalcoholic fatty liver disease (NAFLD). Although the exact molecular pathway leading to impaired insulin signaling has not been

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