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Antifungal saponins from Paris polyphylla Smith.

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Three steroidal saponins, including one new and two known compounds, were isolated from the rhizomes of Paris polyphylla Smith. One- and two-dimensional NMR, LC-MS, and interpretation of hydrolytic cleavage experiments led to the identification of the structure of the new saponin as (

Scytalidiosis in Paris, France.

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BACKGROUND Scytalidium dimidiatum and S hyalinum are molds responsible for human skin and nail infections in tropical areas. OBJECTIVE We sought to examine the epidemiology of cutaneous infections caused by Scytalidium species in a temperate country. METHODS We conducted a retrospective study of

Characteristics and prognosis of sudden cardiac death in Greater Paris: population-based approach from the Paris Sudden Death Expertise Center (Paris-SDEC).

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OBJECTIVE Sudden cardiac death (SCD) is a major public health concern, but data regarding epidemiology of this disease in Western European countries are outdated. This study reports the first results from a large registry of SCD. METHODS A population-based registry was established in May 2011 using

[Pediatric therapeutics and school attendance. Paris, March 1979].

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[Medicen Paris Région: A world-class ''competitiveness cluster'' in the Paris region incorporating a neuroscience ''subcluster''].

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The French public-private partnerships known as "competitive clusters" [pôles de compétitivité (PdC)] are intended to be novel and ambitious engines of regional growth, employment and biomedical innovation. Partly funded by government and local councils, they aim to capitalize on regional expertise

Systemic therapeutic gene delivery for cancer: crafting Paris' arrow.

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Tremendous strides have been made in proteogenomics and RNA interference technologies. Hence "personalized" cancer gene therapy has become a foreseeable rather than a predictable reality. Currently, the lack of an optimized, systemic gene delivery vehicle remains a key limiting factor for developing

Imported malaria in a hospital in Paris.

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The number of cases of imported malaria diagnosed by the Parasitology Laboratory of the Pitié-Salpêtrière Hospital Group in Paris has shown a significant increase in recent years. From 1970 to 1979, 443 cases were diagnosed and the annual number recorded during this period rose from seven to 93

[Faculte de Medecine de Paris. Chair of Therapeutics. Inaugural lecture].

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[Use of topical fungicides in dermatology. Paris, 7 March 1990].

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PARI overexpression promotes genomic instability and pancreatic tumorigenesis.

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Treatment options for patients with pancreatic ductal adenocarcinoma (PDAC) remain limited. Therapeutic targets of interest include mutated molecules that predispose to pancreatic cancer such as KRAS and TP53. Here, we show that an element of the homologous recombination pathway of DNA repair, the

[End-stage cardiac failure: therapeutic strategies. Paris, 29 February-1 March 1996].

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[Faculte de Medecine de Paris. Chair of Clinical Surgical Therapeutics. Inaugural lecture].

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[Neuromeningeal tuberculosis in northeastern suburbs of Paris. Nineteen cases].

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METHODS Analyze characteristics of neuromeningeal tuberculosis in the northeastern suburbs of Paris. METHODS Retrospective study of 19 observations between 1988 and 1999. RESULTS Thirteen cases of meningitis, 3 cases of meningitis associated with a tuberculoma and 3 cases with isolated tuberculoma

[Epidemiologic, clinical and therapeutic analysis of 427 cases of anguilluliasis seen in Paris].

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The authors report 427 cases of strongyloidasis detected in Paris, and emphasize the following points: --High incidence amongst black africans coming from West Africa (17%) ana black carribeans living in France (28.5%). --Lack of hypereosinophilia in two third of cases. --High incidence of

[PARI-ETLD (Therapeutic Approach and Nursing Research -- Epidemiology and Treatment of Decubitus Lesions].

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Pressure sores are one of the preferred nursing research topics but, in spite of the large number of studies, most questions related to the prevention and treatment of pressure sores remain unanswered. Well designed clinical trials and on sufficiently large samples are very rare and most treatments

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