periapical periodontitis/phosphatase

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Chronic alcohol consumption changes blood marker profile and bone density in rats with apical periodontitis.

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The aim of the present study was to evaluate apical periodontitis (AP) development in rats under a chronic alcohol diet by calcium, phosphorus, and alkaline phosphatase blood levels in addition to histological and radiographic analyses.Thirty-two rats were

Dual Role of 5-Lipoxygenase in Osteoclastogenesis in Bacterial-induced Apical Periodontitis.

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BACKGROUND The aim of this study was to evaluate the role of 5-lipoxigenase (5-LO) in the signaling for osteoclast formation and bone resorption in apical periodontitis (AP) after root canal contamination with oral bacteria. METHODS AP was experimentally induced in C57BL/6 mice because of

Association between Increased Inducible Costimulator/Inducible Costimulator Ligand Expression with Bone Destruction in Apical Periodontitis.

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The aim was to assess the association of inducible costimulator (ICOS) and ICOS ligand with bone destruction in apical periodontitis (AP).Specimens from patients presenting with AP were obtained during apicoectomy and subjected to histopathologic analysis

Berberine mediates root remodeling in an immature tooth with apical periodontitis by regulating stem cells from apical papilla differentiation

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Once pulp necrosis or apical periodontitis occurs on immature teeth, the weak root and open root apex are challenging to clinicians. Berberine (BBR) is a potential medicine for bone disorders, therefore, we proposed to apply BBR in root canals to enhance root repair in immature teeth. An in vivo

Alveolar bone remodeling in the early stage of experimental apical periodontitis in the rat mandible.

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Apical periodontitis was surgically induced in the mandibular first molar of rats and chronological changes in the periapical bone tissue were observed by histochemistry and electron microscopy. On the second postoperative day (Day 2), tartrateresistant acid phosphatase (TRACPase)-positive cells

Influence of oestrogen deficiency on the development of apical periodontitis.

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OBJECTIVE To evaluate the effects of a long period of oestrogen deficiency on the development of apical periodontitis in rats. METHODS Wistar rats (n = 24), 3 months old, evaluated by vaginal cytology, were included in the study. Twelve animals were ovariectomized (OVX group) and the other 12 were

The influence of adrenergic blockade in rats with apical periodontitis under chronic stress conditions.

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To investigate the influence of chronic stress and adrenergic blockade in a rat model of apical periodontitis.Thirty-two Wistar rats were submitted to an animal model of periapical lesion and randomly divided into 4 groups (n = 8): no stress (NS); stress +

Comparison of apical periodontitis repair in endodontic treatment with calcium hydroxide-dressing and aPDT.

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This study evaluated the effect of antimicrobial photodynamic therapy (aPDT) on the endodontic treatment of apical periodontitis (AP). AP was induced in 48 premolars of 6 dogs. After biomechanical preparation, the teeth were divided into 4 groups: Calcium-Hydroxide (CH)/120d and CH/180d: root canals

Reduced bone resorption and inflammation in apical periodontitis evoked by dietary supplementation with probiotics in rats

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Aim: To evaluate the relationship between systemic administration of probiotics and inflammation/resorption processes associated with apical periodontitis (AP) in a rat model. Methodology:

Tissue response to root canal irrigation systems in dogs' teeth with apical periodontitis.

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OBJECTIVE The aim of this study was to compare the efficacy of apical negative pressure irrigation (ANP) and passive ultrasonic irrigation (PUI) with apical positive pressure irrigation (PP-conventional irrigation) in the periapical repair of dogs' teeth with apical periodontitis. METHODS Forty-nine

MMP9 deficiency increased the size of experimentally induced apical periodontitis.

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BACKGROUND Apical periodontitis is an inflammation and destruction of periapical tissues. Matrix metalloproteinase-9 (MMP-9) is thought to be involved in periapical lesion formation and progression. The aim of this study was to evaluate the lesion progression in MMP-9 knockout (KO) mice compared

Omega 3 Fatty Acids Reduce Bone Resorption While Promoting Bone Generation in Rat Apical Periodontitis.

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BACKGROUND This study evaluated the effects of the dietary supplement omega 3 polyunsaturated fatty acids (ω-3 PUFAs) on pulp exposure-induced apical periodontitis (AP) in rats. METHODS Twenty-eight male rats were divided into groups: control untreated rats (C), control rats treated with ω-3 PUFAs

5-Lipoxygenase Knockout Aggravated Apical Periodontitis in a Murine Model.

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5-Lipoxygenase (5-LO) plays a vital role in the host innate immune response, including bacteria-induced inflammation. Apical periodontitis (AP) is due to immune disorders caused by imbalances between bacterial invasion and subsequent host defense response. In this work, we investigated the role of

Effects of 5-lipoxygenase gene disruption on inflammation, osteoclastogenesis and bone resorption in polymicrobial apical periodontitis.

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To investigate the regulation of inflammatory and osteoclastogenic signaling by 5-lipoxygenase (5-LO) in apical periodontitis induced by oral contamination of dental root canals in mice.

DESIGN

Apical periodontitis was induced in 5-lipoxygenase enzyme

NLRP12 Attenuates Inflammatory Bone Loss in Experimental Apical Periodontitis.

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Apical periodontitis is an inflammatory disorder that results from the host immune response to microbial infection through the dental pulp, leading to alveolar bone destruction. The nod-like receptor 12 (NLRP12) is an atypical intracellular sensor of the NLR family that is involved in the negative

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