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periapical periodontitis/protease

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ArticoleStudii cliniceBrevete
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We isolated spore-forming gram-positive aerobic rods from three patients with persistent periapical periodontitis. These cells possessed unique phenotypic characteristics by exhibiting dense meshwork-like structures on their cell surfaces that could be found in a number of biofilm-forming bacteria.
BACKGROUND Cytolytic Enterococcus faecalis possesses a highly toxic and proinflammatory capacity. Cytokines and proteases play important roles in the host inflammatory response. The aim of this study was to compare the local expression of interleukin (IL)-1β and matrix metalloproteinase-8 (MMP-8)
OBJECTIVE To measure the release of hydrolytic enzymes [elastase, cathepsin G and collagenase-2 (MMP-8)] from human polymorphonuclear leukocytes (PMNs) during interaction with strains of Enterococcus faecalis isolated from endodontic infections. METHODS Six E. faecalis strains isolated from

Metaproteome analysis of endodontic infections in association with different clinical conditions.

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Analysis of the metaproteome of microbial communities is important to provide an insight of community physiology and pathogenicity. This study evaluated the metaproteome of endodontic infections associated with acute apical abscesses and asymptomatic apical periodontitis lesions. Proteins persisting

Proteomic analysis of endodontic infections by liquid chromatography-tandem mass spectrometry.

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BACKGROUND Endodontic infections are very prevalent and have a polymicrobial etiology characterized by complex interrelationships between endodontic microorganisms and the host defenses. Proteomic analysis of endodontic infections can provide global insights into the invasion, pathogenicity

Effect of Enterococcus faecalis lipoteichoic acid on apoptosis in human osteoblast-like cells.

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BACKGROUND Enterococcus faecalis is commonly detected in persistent apical periodontitis characterized by unimproved periradicular bone resorption. The aim of the present study was to examine the effect of lipoteichoic acid (LTA), a major virulence factor of E. faecalis, on apoptosis of
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