puerarin/hemoragie

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[Effects of puerarin on the vascular active factor related to cerebral vasospasm after aneurysm subarachnoid hemorrhage].

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OBJECTIVE To investigate the effects and possible mechanisms of puerarin on the vascular active factors correlated to cerebral vasospasm (CVS) after aneurysm subarachnoid hemorrhage (aSAH). METHODS Fifty-four patients with aSAH were randomly assigned to the puerarin group (30 cases) and the control

Puerarin attenuates neurological deficits via Bcl-2/Bax/cleaved caspase-3 and Sirt3/SOD2 apoptotic pathways in subarachnoid hemorrhage mice.

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Subarachnoid hemorrhage (SAH) results in many brain dysfunctions and the neuroprotective function of puerarin after brain damage has been demonstrated in several studies. But whether puerarin can reduce brain nerve damage after SAH is not clear.In this study, we hypothesized that

[Effect of catalpol and puerarin freeze-dried powder on coagulability, hemorheology and no in rats with Qi-deficiency and blood-stasis syndrome].

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OBJECTIVE To study the effect of catalpol and puerarin freeze-dried powder for injection (CPFPI), a new compound traditional Chinese medicine (TCM) preparation, on coagulability, hemorheology and NO in rats with qi-deficiency and blood-stasis syndrome. METHODS The model of rats with qi-deficiency

Clinical efficacy and CT perfusion of puerarin combined with naloxone in the treatment of traumatic cerebral infarction.

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Puerarin is an important active ingredient of Radix puerariae. Puerarin is an isoflavone compound Z clinical and basic research proves that S. puerarin can increase cerebral circulation blood flow; increase cerebral perfusion; reduce blood viscosity and improve microcirculation. The present research

Comparison on anticoagulation and antiplatelet aggregation effects of puerarin with heparin sodium and tirofiban hydrochloride: an in Vitro study.

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OBJECTIVE To detect the anticoagulation and antiplatelet effects of different concentrations of puerarin, heparin sodium and tirofiban hydrochloride on the blood samples of healthy volunteers by Sonoclot coagulation and platelet function analyzer. METHODS Peripheral blood samples were extracted from

Synergistic Effects of Salvianolic Acid B and Puerarin on Cerebral Ischemia Reperfusion Injury.

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Ischemic stroke (IS) is characterized by the sudden loss of blood circulation to an area of the brain, resulting in a corresponding loss of neurologic function. It has been a worldwide critical disease threatening to the health and life of human beings. Despite significant progresses achieved,

Puerarin attenuates cisplatin-induced rat nephrotoxicity: The involvement of TLR4/NF-κB signaling pathway.

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Puerarin was a major isoflavonoid derived from the Chinese medical herb radix puerariae (Gegen). In present study effect of puerarin on cisplatin nephrotoxicity was evaluated. Rat model of nephrotoxicity was established by a single intraperitoneal injection of cisplatin (7mg/kg). Puerarin was

Puerarin inhibits inflammation and oxidative stress in dextran sulfate sodium-induced colitis mice model.

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Ulcerative colitis (UC) is an inflammatory bowel disease accompanied by abdominal pain, diarrhea, and rectal bleeding. The aim of this study was to investigate whether puerarin, one of the main components of the root of Pueraria lobata, exerts anti-inflammatory and anti-oxidative effects against UC.

Interaction Between Traditional Chinese Medicine and Anticoagulant/antiplatelet Drugs.

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Traditional Chinese Medicine (TCM) has been used for medical purposes since the ancient time and has gradually gained recognition worldwide. Nowadays, patients with thrombus presiding to anticoagulant/antiplatelet drugs prefer taking TCM. However, an increasing number of studies on

Single herbal medicine for diabetic retinopathy.

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Diabetic retinopathy is one of the major causes of blindness and the number of cases has risen in recent years. Herbal medicine has been used to treat diabetes and its complications including diabetic retinopathy for thousands of years around the world. However, common practice is not

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