rutinose/inflamație

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Enzyme-mediated transglycosylation of rutinose (6-O-α-l-rhamnosyl-d-glucose) to phenolic compounds by a diglycosidase from Acremonium sp. DSM 24697.

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The structure of the carbohydrate moiety of a natural phenolic glycoside can have a significant effect on the molecular interactions and physicochemical and pharmacokinetic properties of the entire compound, which may include anti-inflammatory and anticancer activities. The enzyme

Hesperidin suppresses ovalbumin-induced airway inflammation in a mouse allergic asthma model.

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Hesperidin, a flavanone glycoside comprised of the flavanone hesperetin and the disaccharide rutinose, is a plentiful and inexpensive by-product of citrus cultivation. It has been reported to exert a wide range of pharmacological effects that include antioxidant, anti-inflammatory, and

Interference of some flavonoids and non-steroidal anti-inflammatory drugs with oxidative metabolism of arachidonic acid by human platelets and neutrophils.

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The effect of ten flavonoids was studied on the stimulation of washed human platelets by either arachidonic acid or thrombin. The oxygenated metabolites released were analyzed by radioimmunoassay, glass-capillary-column gas chromatography and high-pressure liquid chromatography. No effect was

Anti-inflammatory effect of heme oxygenase 1: glycosylation and nitric oxide inhibition in macrophages.

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Flavonoids including the aglycones, hesperetin (HT; 5,7,3'-trihydroxy-4'-methoxy-flavanone), and naringenin (NE; 5,7,4'-trihydroxy flavanone) and glycones, hesperidin (HD; 5,7,3'-trihydroxy-4'-methoxy-flavanone 7-rhamnoglucoside) and naringin (NI; 5,7,4'-trihydroxy flavanone 7-rhamno glucoside),

Rutin prevents the ovariectomy-induced osteoporosis in rats.

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Our study aimed to explore the anti-osteoporotic effect of rutin (quercetin-3-O-rutinose) on ovariectomized female rats. An ovariectomized (OVX) rat model of osteoporosis was employed to evaluate the anti-osteoporotic potency of rutin. One week after surgery, the rats were administered

[HPLC investigation of antioxidant components in Solidago herba].

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Representatives of Solidago species have been used in European phytotheraphy for centuries as a component of urological and antiphlogistical remedies. Solidago canadensis L. (Asteraceae) contains a wide range of active ingredients, such as flavonoids, saponins, hydroxycinnamates and mineral

Differential apoptosis-inducing effect of quercetin and its glycosides in human promyeloleukemic HL-60 cells by alternative activation of the caspase 3 cascade.

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Flavonoids were demonstrated to possess several biological effects including antitumor, antioxidant, and anti-inflammatory activities in our previous studies. However, the effect of glycosylation on their biological functions is still undefined. In the present study, the apoptosis-inducing

Rutin as neuroprotective agent: from bench to bedside.

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Flavonoids are major dietary constituents of plant-based food that occur ubiquitously in plant kingdom where they are usually present in substantial amounts. Rutin is a flavonol-type polyphenol and consists of the flavonol quercetin and the disaccharide rutinose. Rutin has been reported to exert

[Health--promoting effect of quercetin in human diet].

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Quercetin is a plant flavonoid phytochemical exhibiting a broad spectrum of properties i.a. antioxidant, anti-inflammatory and immunomodulatory. However, the effect of quercetin is not clear. This compound at low concentrations can stimulate proliferation of human cells, so it can be a potential

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