scrub typhus/seizures

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Central nervous system involvement in scrub typhus.

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Scrub typhus is an emerging infectious disease in India. Among its protean clinical manifestations, central nervous system involvement is common. In this prospective observational study, altered sensorium, headache, seizures and aseptic meningitis were found to be common central nervous system

Scrub typhus meningitis: An under-recognized cause of aseptic meningitis in India.

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BACKGROUND Central nervous system (CNS) involvement in scrub typhus is seen in up to a quarter of patients. However, the literature on cerebrospinal fluid (CSF) analysis and outcome in meningitis/meningo-encephalitis due to scrub typhus is scant. METHODS This retrospective study included patients

Haemorrhagic encephalitis in the garb of scrub typhus

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A 19-year-old girl presented with fever, headache, vomiting and drowsiness. She had grade 1 papilloedema and neck rigidity but no focal deficits or seizures. Cerebrospinal fluid analysis revealed lymphocytic pleocytosis, slightly elevated protein and normal glucose. MRI of the brain showed a

Triple trouble--macrophage activation syndrome in a case of severe leptospirosis and scrub typhus co-infection.

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Macrophage activation syndrome is a potentially life threatening phenomenon characterised by aggressive proliferation of macrophages and T lymphocytes leading to haemophagocytosis of other blood cells and multi organ failure. Here we present a very unusual combination of leptospirosis and scrub

Life-threatening scrub typhus with meningoencephalitis and acute respiratory distress syndrome.

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A 21-year-old man presented with fever, rash, seizure, stiff neck and rapidly progressive bilateral pulmonary infiltrates. Cerebrospinal fluid (CSF) study revealed pleocytosis with predominant polymorphonuclear cells, and hypo-glycorrhachia. Status epilepticus occurred, followed by acute respiratory

Meningoencephalitis, myocarditis and disseminated intravascular coagulation in a patient with scrub typhus.

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A 21-year-old male soldier was admitted due to a sore throat, headache, generalized lymphadenopathy and persistent fever for 12 days. Despite empirical antibiotic treatment for four days at a clinic prior to admission, he continued to have persistent abdominal pain over his right upper quadrant

Central Nervous System Infection Associated with Orientia tsutsugamushi in South Korea.

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Orientia tsutsugamushi is a major cause of vector-borne infection in Asia. Prompt recognition and appropriate treatment are crucial because of its potentially fatal complications and lack of response to beta-lactam antibiotics. The present study retrospectively evaluated the clinical characteristics

Outbreak of scrub typhus in Andhra Pradesh--experience at a tertiary care hospital.

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OBJECTIVE To describe the clinical features, laboratory manifestations, complications in patients diagnosed with scrub typhus at a tertiary care hospital in south India. METHODS All cases of acute onset fever diagnosed to have scrub typhus August 2011 to December 2012 were analysed. Cases of scrub

Scrub typhus meningoencephalitis, a diagnostic challenge for clinicians: A hospital based study from North-East India.

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Central nervous system (CNS) involvement is a known complication of scrub typhus which range from mild meningitis to frank meninigoencephalitis. OBJECTIVE To study the clinical feature, laboratory parameters and response to treatment of scrub typhus meningitis/meningoencephalitis. METHODS This is a

Acute encephalitis syndrome following scrub typhus infection.

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OBJECTIVE The aim was to find the incidence of acute encephalitis syndrome (AES) secondary to scrub infection and to observe the clinical, biochemical, radiological profile, and outcomes in these patients. METHODS A total of 20 consecutive patients of AES were evaluated for scrub infection using

Scrub Typhus Leading to Acute Liver Failure in a Pregnant Patient

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Scrub typhus is a mite-borne rickettsial infection that presents with fever and a diverse array of complications. Lately, many epidemics have been reported from the Indian subcontinent. Data from these outbreaks suggest that liver injury in scrub typhus is common and reversible. We are reporting the

Neurological manifestations of scrub typhus in adults.

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In order to study the neurological manifestations in adult patients suffering from scrub typhus, 323 patients aged over 18 years, admitted with a positive diagnosis, were screened for neurological dysfunction; 37 patients with symptoms and/or signs suggestive of neurological dysfunction were

Comparison of Scrub Typhus With and Without Meningitis.

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OBJECTIVE To compare the children admitted with scrub typhus with and without meningitis. METHODS All children admitted with scrub typhus over a 62 mo period were reviewed. Statistical analysis was performed to compare those with and without meningitis for demographic, clinical, investigations and

Scrub Typhus: A Clinico-Laboratory Differentiation of Children with and without Meningitis.

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Neurological involvement in the form of meningitis or meningoencephalitis, although well documented in scrub typhus, has not been extensively studied in the pediatric population. We report the clinical and laboratory profile of 96 children with scrub typhus and compared those with and without

Clinical profile, complications and outcome of scrub typhus in children: A hospital based observational study in central Nepal.

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Scrub typhus, an important cause of unexplained fever, is grossly neglected and often misdiagnosed in low and middle income countries like Nepal. The main aim of this study was to report on the clinical profile and complications of scrub typhus and its outcome in Nepalese

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