sennosides a/senna

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Sennosides A and B production by hairy roots of Senna alata (L.) Roxb.

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Hairy roots of Senna alata transformed with Agrobacterium rhizogenes, strain ATCC 15834 were induced and grown in half-strength Murashige and Skoog (MS) medium. Effects of sucrose contents and hormones on the growth and sennosides A, B production were investigated. Hairy roots cultured on

Comparison on extraction yield of sennoside A and sennoside B from senna (Cassia angustifolia) using conventional and non conventional extraction techniques and their quantification using a validated HPLC-PDA detection method.

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Senna is an important medicinal plant and is used in many Ayurvedic formulations. Dianthraquinone glucosides are the main bioactive phytochemicals present in leaves and pods of senna. The extraction efficiency in terms of yield and composition of the extract of senna prepared using both conventional

Validated HPLC method for determination of sennosides A and B in senna tablets.

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This study developed an efficient and reliable ion-pair liquid chromatographic method for quantitation of sennosides A and B in commercial senna tablets. Separation was conducted on a Hypersil C 18 column (250 x 4.6 mm, 5 microm) at a temperature of 40 degrees C, using a mixture of 0.1 M acetate

Isolation of a new aloe-emodin dianthrone diglucoside from senna and its potentiating effect on the purgative activity of sennoside A in mice.

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Two aloe-emodin dianthrone diglucosides (I and II) were isolated from the leaves of Cassia angustifolia Vahl by successive column chromatography with Amberlite XAD-2, silica gel, Polyamide C-200 and Sephadex LH-20. The stereostructures of I and II were elucidated as trans and meso isomers at 10-10',

Aquaporins Alteration Profiles Revealed Different Actions of Senna, Sennosides, and Sennoside A in Diarrhea-Rats.

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Senna and its main components sennosides are well-known effective laxative drugs and are used in the treatment of intestinal constipation in the world. Their potential side effects have attracted more attention in clinics but have little scientific justification. In this study, senna extract (SE),

[Mechanism of action of senna anthraglucosides; sennosides A and B].

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[Mechanism of action of the anthraglucosides of Senna, sennosides A & B].

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Estimation of sennosides A, B, C and D in Senna leaves, pods and formulations.

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[Quantitative chromatographic determination of the active principles of senna (sennoside A, sennoside B)].

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A cosmetic senna, Cassia obovata: 'neutral henna'.

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Summary The powder made with leaflets of a senna, Cassia obovata Coll., is a cosmetic mis-called 'neutral henna' The traditional use of C. obovata is as a laxative. The principal active components of this laxative drug are sennosides A and B. In the Middle Ages the blend of henna (Lawsonia inermis)

Simultaneous separation of three isomeric sennosides from senna leaf (Cassia acutifolia) using counter-current chromatography.

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Senna leaf is widely consumed as tea to treat constipation or to aid in weight loss. Sennoside A, A1 , and B are dirheinanthrone glucosides that are abundant and the bioactive constituents in the plant. They are isomers that refer to the (R*R*), (S*S*), and (R*S*) forms of protons on C-10 and C-10'

The senna drug and its chemistry.

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Senna consists of the dried leaflets or fruits of Cassia senna (C. acutifolia) known in commerce as Alexandrian senna and of Cassia angustifolia commonly known as Tinnevelly senna. The senna plants are small shrubs of Leguminosae cultivated either in Somalia, the Arabian peninsula and near the Nile

Two low-dose bowel-cleansing regimens: efficacy and safety of senna and sodium phosphorus solution for colonoscopy.

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BACKGROUND The aim of the present study was to compare the efficacy, adequacy, side effects, and patient compliance of sodium phosphorus (NaP) and senna solutions when preparing the colon before colonoscopy. METHODS A total of 137 consecutive patients who were considered for colonoscopy evaluation

Ion-pair partition chromatography analysis of anthraquinone glycosides of senna and pharmaceutical preparations of senna.

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Ion-pair partition has been combined with HPLC for the rapid detection and separation of the major anthraquinone glycosides of senns, sennosides A and B. A Corasil C18 column (5 microns) with methyl alcohol (30 percent in water) containing 0.005 M tetrabutylammonium phosphate, pH 7.5, as mobile

Transport of sennosides and sennidines from Cassia angustifolia and Cassia senna across Caco-2 monolayers--an in vitro model for intestinal absorption.

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Laxative effects of Senna preparations are mainly mediated by rheinanthrone, a metabolite formed in the intestinal flora from dianthrones. Nevertheless, it was not clear whether dianthrones are bioavailable at all and contribute to the overall effects of this important medicinal plant. Using the

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