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Age associated clinical manifestations of systemic lupus erythematosus: a multivariate regression analysis.

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The influence of age on the prevalence of individual clinical manifestations of systemic lupus erythematosus (SLE) has not been adequately distinguished from racial or gender influences. Therefore, we examined variations in the clinical manifestations of SLE with age in a group of 361 patients.

Complete atrioventricular block as initial manifestation of systemic lupus erythematosus.

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Only a few cases of complete atrioventricular block (AVB) in adult lupus patients have been previously described, but only one as the initial manifestation. A 19-year-old woman who presented with seizures and loss of consciousness, was diagnosed with complete ABV and underwent pacemaker placement.

Systemic lupus erythematosus in Pakistan.

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Clinical features of systemic lupus erythematosus (SLE) have been described from different geographical regions in the world, with some clinical differences among different racial groups. Although data on the characteristics of SLE in Pakistan is scarce, it is not uncommon in the South East Asian

Association between SLE nephritis and polymorphic variants of the CRP and FcgammaRIIIa genes.

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OBJECTIVE To study the relationship between clinical manifestations in systemic lupus erythematosus (SLE) with polymorphisms in suggested susceptibility genes encoding FcgammaRIIa, FcgammaRIIIa, FcgammaRIIIb, CRP and IL-1Ra. METHODS Genetic polymorphisms were analysed in 323 unrelated SLE patients

Clozapine safety, 40 years later.

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Clozapine is, and will remain in the coming years, an irreplaceable drug in psychiatry which has elective indication in treatment-resistant schizophrenia, suicide risk in schizophrenia spectrum disorders, aggressiveness or violence in psychiatric patients, psychosis in Parkinson's disease,

Encephalic large arteries narrowness and peripheral neuropathy in a patient with adult-onset Still's disease.

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Adult-onset Still's disease (AOSD) is a rare, systemic inflammatory disorder, characterized by spiking high fever, fever-associated evanescent rash, arthritis, myalgia, serositis and hepatosplenomegaly. White blood cell count, neutrophilic cell count, and serum ferritin level are markedly elevated

Systemic lupus erythematosus in India.

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The first case of systemic lupus erythematosus (SLE) was reported from India in 1995 followed by two more case reports and further, a series of eight cases, till 1969. Since the establishment of a clinical immunology laboratory at a major teaching institution in New Delhi in 1968, SLE was

Prevalence of IgA deficiency in adult systemic lupus erythematosus and the study of the association with its clinical and autoantibody profiles.

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BACKGROUND IgA deficiency (IgAD) is the most common primary immunodeficiency, which can cause frequent infections. The association of IgA deficiency with systemic lupus erythematosus (SLE) is very important because of the high morbidity and mortality rates of infections in patients with this

Fatal lupus pleuritis presenting in pregnancy. A case report.

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BACKGROUND Lupus, one of the most common autoimmune diseases in pregnancy, may involve multiple organ systems with varying severity. The diagnosis and treatment of the disease may be complicated by the physiologic changes of pregnancy. METHODS A 22-year-old woman presented at 29 weeks' gestation

[Psychiatric manifestations of autoimmune diseases--diagnostic and therapeutic problems].

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In autoimmune diseases, also called connective tissue diseases, many systems and organs are involved, including the central, peripheral and autonomic nervous system. The frequency of neurological and neuropsychiatric manifestations varies in certain autoimmune diseases. One of the most common causes

[Studies on clinical subsets and severity of systemic lupus erythematosus based on a 1987 questionnaire conducted in Japan--clinical analysis of the outcome and treatments in clinical subsets].

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A 1987 questionnaire sponsored by the Health and Welfare Ministry concerning the clinical subsets and severity of systemic lupus erythematosus (SLE) was distributed to 93 medial facilities. A clinical analysis of the outcome and treatments was accomplished on one thousand six hundred and fourteen

Factors associated with active systemic lupus erythematosus after endstage renal disease.

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OBJECTIVE Activity of systemic lupus erythematosus (SLE) often declines after patients reach endstage renal disease (ESRD). However, extrarenal activity is not uncommon, especially during the first few years of dialysis. We reviewed the clinical course of SLE patients with ESRD treated in our unit

Gender differences in systemic lupus erythematosus.

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BACKGROUND Systemic lupus erythematosus (SLE) is known to be much more prevalent in females than in males, but the cause of this sexual predilection is not established. In addition, much controversy surrounds the differences in manifestations of SLE in both sexes. OBJECTIVE This article reviews the

Haemolytic anaemia in a multi-ethnic cohort of lupus patients: a clinical and serological perspective.

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Systemic lupus erythematosus is a chronic autoimmune disease that can be associated with a variety of haematological manifestations. We identified 76 patients with haemolytic anaemia in a cohort of 1251 unrelated female lupus patients enrolled in our studies. The presence of the various American

Mortality risks associated with specific clinical manifestations of systemic lupus erythematosus.

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BACKGROUND Mortality in patients with systemic lupus erythematosus (SLE) is often related to disease in particular organ systems. We examined the risks of mortality associated with 8 clinical manifestations of SLE and determined whether these risks differed among patients with different

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