vitamin p/inflamație

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[Vitamin P and inflammations].

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[On the effect of substances with vitamin P activity on inflammation and acute tissue edema].

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[Anti-inflammatory properties of flavonoids].

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Flavonoids are widely spread in plant kingdom. Since the works of Rusznyak and Szent-Gyorgyi (1936), they are mainly used as vitamin P like agents. Nevertheless, other properties have been discovered, among these the anti-inflammatory activity. Hypolaetin 8-glucoside and some other anti-inflammatory

Hesperidin protects against IL-1β-induced inflammation in human osteoarthritis chondrocytes.

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Hesperidin is a vitamin P flavonoid compound primarily present in citrus fruits, which possesses an anti-inflammatory effect. The functional role of hesperidin in interleukin (IL)-1β-stimulated human osteoarthritis (OA) chondrocytes is still unknown. In the present study, anti-inflammatory effects

The association between high sensitivity C-reactive protein and micronutrient levels: A cross-sectional analysis based on a laboratory database.

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Low-grade chronic inflammation is a condition underlying many serious diseases but there is no good single biomarker which can estimate and monitor the severity of the inflammation. C-reactive protein (CRP) is the best validated and most extensively used marker. The aims of the study

Beneficial effects of antioxidant vitamins on the stenotic kidney.

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Renal artery stenosis (RAS) may lead to renal injury, partly mediated through increased oxidative stress. However, the potential effects of chronic oral antioxidant intervention on the stenotic kidney remain unknown. This study was designed to test the hypothesis that chronic antioxidant vitamin

Protective effect of rutin on LPS-induced acute lung injury via down-regulation of MIP-2 expression and MMP-9 activation through inhibition of Akt phosphorylation.

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Lipopolysaccharide (LPS), also called endotoxin, is the important pathogen of acute lung injury (ALI), which is a clinical syndrome that still lacks effective therapeutic medicine. Rutin belongs to vitamin P and possesses various beneficial effects. In this study, we investigate the potential

Comparison of acute and chronic antioxidant interventions in experimental renovascular disease.

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Reactive oxygen species (ROS) can modulate renal hemodynamics and function both directly, by leading to vasoconstriction, and indirectly, by inducing renal inflammation and tissue growth. The involvement of oxidative stress in the pathogenesis of renovascular disease (RVD) is increasingly

Rutin protects dopaminergic neurons from oxidative stress in an animal model of Parkinson's disease.

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This study was undertaken to investigate the neuroprotective effects of rutin (vitamin P) on 6-hydroxydopamine (6-OHDA)-induced Parkinson's disease (PD) in rats. Oxidative stress and inflammation is an important event, play a crucial role in neurodegenerative diseases. Rutin has been shown to have

Alterations of bone mineral density and bone metabolism in patients with various grades of chronic pancreatitis.

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The aim of this study was to examine bone mineral density (BMD) and bone metabolism in patients with chronic pancreatitis to determine if increased severity of the disease would correlate with increased bone loss. Between October 1999 and September 2000, we investigated 42 patients with an average

Review of the protective effects of rutin on the metabolic function as an important dietary flavonoid.

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BACKGROUND In recent years, flavonoids have been revealed to be helpful in the treatment of many diseases. Rutin (3,3',4',5,7-pentahydroxyflavone-3-rhamnoglucoside) is an important flavonoid that is consumed in the daily diet. It is also known as vitamin P and quercetin-3-O-rutinoside. In addition,

Antioxidant intervention blunts renal injury in experimental renovascular disease.

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Atherosclerotic renovascular disease (RVD) amplifies damage in a stenotic kidney by inducing pro-inflammatory mechanisms and disrupting tissue remodeling. Oxidative stress is increased in RVD, but its direct contribution to renal injury has not been fully established. The authors hypothesized that

Rutin prevents cognitive impairments by ameliorating oxidative stress and neuroinflammation in rat model of sporadic dementia of Alzheimer type.

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The objective of the present study was to assess the neuroprotective role of rutin (vitamin P) and delineate the mechanism of action. Recent evidence indicates that rutin exhibits antioxidant potential and protects the brain against various oxidative stressors. More precisely, the aim of the present

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