vulvodynia/cefalee

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Vulvodynia: new thoughts on a devastating condition.

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Vulvodynia affects 3% to 15% of women; many suffer through years of misdiagnosis and for those who receive care cures are uncommon. Little is known about the etiology and a wide range of therapeutic options are available. With treatment approximately 50% of women will report sustained improvement in

Study on the prevalence and factors associated to vulvodynia in Spain.

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To study the prevalence and epidemiological characteristics of women with vulvodynia. To assess the risk factors associated to the disease.A cross-sectional study was made in which questionnaires were anonymously and confidentially distributed to Spanish

Nitric oxide: new evidence for novel therapeutic indications.

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BACKGROUND Nitric oxide (NO) deficiency is implicated in many pathophysiological processes in mammals. NO is a ubiquitous molecule involved in multiple cellular functions. Uncontrolled or inappropriate production of NO may lead to several disease states including septic shock, rheumatoid and

Vulvar pain: The revealing scenario of leading comorbidities in 1183 cases

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Objectives: This study set out to investigate the epidemiological characteristics and comorbidities of chronic vulvar pain. Secondary goals were to identify the preferred approaches for managing vulvodynia in Italy.

MicroRNA expression profiles differentiate chronic pain condition subtypes.

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Chronic pain is a significant health care problem, ineffectively treated because of its unclear etiology and heterogeneous clinical presentation. Emerging evidence demonstrates that microRNAs (miRNAs) regulate the expression of pain-relevant genes, yet little is known about their role in chronic

Co-occurrence of Pain Symptoms and Somatosensory Sensitivity in Burning Mouth Syndrome: A Systematic Review.

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BACKGROUND Burning mouth syndrome (BMS) is a chronic and spontaneous oral pain with burning quality in the tongue or other oral mucosa without any identifiable oral lesion or laboratory finding. Pathogenesis and etiology of BMS are still unknown. However, BMS has been associated with other chronic

The association between exposure to childhood maltreatment and the subsequent development of functional somatic and visceral pain syndromes

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Background: Childhood maltreatment is a global public health issue linked to a vast mortality and morbidity burden. This study builds on current literature to explore the risk of developing central sensitivity syndromes (CSS) (consisting

Editorial review: an update on central sensitivity syndromes and the issues of nosology and psychobiology.

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Central sensitization (CS), simply defined as an amplified response of the central nervous system to peripheral input, is a concept of great importance in clinical medicine. It has helped to explain aspects of the pathophysiology of common diseases, e.g. fibromyalgia syndrome (FMS), irritable bowel

Prevalence of pain syndromes, mood conditions, and asthma in adolescents and young women with endometriosis.

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OBJECTIVE Adult women with endometriosis are often diagnosed with comorbid pain, mood, and autoimmune conditions. This study aims to describe the occurrence of pain syndromes, mood conditions, and asthma in adolescents and young women with endometriosis evaluated at our medical

Diet and its role in interstitial cystitis/bladder pain syndrome (IC/BPS) and comorbid conditions.

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What's known on the subject? and What does the study add? Nearly 90% of patients with interstitial cystitis/bladder pain syndrome (IC/BPS) report sensitivities to a wide variety of dietary comestibles. Current questionnaire-based literature suggests that citrus fruits, tomatoes, vitamin C,

Psychosocial Vulnerability and Early Life Adversity as Risk Factors for Central Sensitivity Syndromes.

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The aim of this narrative review of the epidemiology of central sensitivity syndromes is to provide a summary of the role of early life adversity and psychosocial / psychological factors, in the epidemiology of six main syndromes: (i) fibromyalgia / chronic widespread pain; (ii) headache / migraine;

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