Energy Expenditure and Body Composition in Pseudohypoparathyroidism 1a
Ключевые слова
абстрактный
Описание
Pseudohypoparathyroidism 1a (PHP1a) is a disorder that is associated with many endocrine problems. People with PHP1a are at risk for the development of obesity. The objective of the study will help determine if obesity is related to abnormalities energy expenditure, meaning that people with PHP1a may not burn as many calories while at rest as those without the disorder.
In order to further evaluate obesity in PHP1a, investigators are planning to measure resting energy expenditure (REE), which is the amount of calories burned while completely at rest. Investigators will also evaluate body composition by looking at measures of growth and development and determining the amount of body fat using dual energy x-ray absorptiometry (DXA) as well as blood and urine biologic markers of obesity. The investigators plan to evaluate people with PHP1a at all weights.
Даты
| Последняя проверка: | 07/31/2018 |
| Первый отправленный: | 07/18/2011 |
| Предполагаемая регистрация отправлена: | 07/19/2011 |
| Первое сообщение: | 07/20/2011 |
| Последнее обновление отправлено: | 08/19/2018 |
| Последнее обновление опубликовано: | 08/21/2018 |
| Фактическая дата начала исследования: | 05/31/2011 |
| Предполагаемая дата завершения начальной школы: | 08/31/2015 |
| Предполагаемая дата завершения исследования: | 11/19/2017 |
Состояние или болезнь
Фаза
Критерии приемлемости
| Возраст, имеющий право на обучение | 5 Years Чтобы 5 Years |
| Полы, имеющие право на обучение | All |
| Метод отбора проб | Non-Probability Sample |
| Принимает здоровых добровольцев | да |
| Критерии | Inclusion Criteria: - Diagnosis of pseudohypoparathyroidism 1a - Any body weight Exclusion Criteria: - Absence of above diagnosis |
Результат
Основные показатели результатов
1. Resting Energy Expenditure [30 minutes]
Меры вторичного результата
1. Characterize body composition in patients with PHP1a. [12 months]
