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Страница 1 от 28 полученные результаты
Cardiovascular responses to sugary drinks in humans: galactose presents milder cardiac effects than glucose or fructose.
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OBJECTIVE
There is increasing interest into the potentially beneficial effects of galactose for obesity and type 2 diabetes management as it is a low-glycemic sugar reported to increase satiety and fat mobilization. However, fructose is also a low-glycemic sugar but with greater blood pressure
Do bubble characteristics affect recanalization in stroke patients treated with microbubble-enhanced sonothrombolysis?
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Administration of microbubbles (MB) may augment the effect of ultrasound-enhanced systemic thrombolysis in acute stroke. Bubble structural characteristics may influence the effect of MB on sonothrombolysis. We aimed to compare the effects of galactose-based air-filled MB (Levovist) and sulphur
Ultrasonic evaluation of pathological brain perfusion in acute stroke using second harmonic imaging.
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OBJECTIVE
To evaluate the use of transient response second harmonic imaging (HI) by means of ultrasound to assess abnormalities of cerebral echo contrast agent enhancement in patients with acute stroke.
METHODS
The study comprised 25 patients with acute onset of hemispheric stroke (<24 h) with
Effect of galactose on systemic hemodynamics and blood flow rate in normal and tumor tissues in rats.
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The effect of galactose on systemic hemodynamics and blood flow rate of Walker 256 carcinomas and several normal tissues of unanesthetized, unrestrained female Sprague-Dawley rats was measured, using the radioactive microsphere technique, prior to and at 30 and 60 min after galactose administration
Nonviability of cells with oxidative defects in galactose medium: a screening test for affected patient fibroblasts.
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Diagnosis of respiratory chain defects in cultured skin fibroblasts is a difficult diagnostic procedure. We investigated the feasibility of using survival of skin fibroblasts in culture medium with galactose as the major carbon source as a method of quickly diagnosing cell lines that were
Ischemic stroke is associated with the pro-inflammatory potential of N-glycosylated immunoglobulin G.
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BACKGROUND
Glycosylation significantly affects protein structure and function and thus participates in multiple physiologic and pathologic processes. Studies demonstrated that immunoglobulin G (IgG) N-glycosylation associates with the risk factors of ischemic stroke (IS), such as aging, obesity,
Microbubble administration accelerates clot lysis during continuous 2-MHz ultrasound monitoring in stroke patients treated with intravenous tissue plasminogen activator.
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OBJECTIVE
We sought to evaluate the effects of administration of microbubbles (MBs) on the beginning, speed, and degree of middle cerebral artery (MCA) recanalization during systemic thrombolysis and continuous 2-MHz pulsed-wave transcranial Doppler (TCD) monitoring.
METHODS
We evaluated 111
Contrast-enhanced transcranial Doppler sonography in patients with acute cerebrovascular diseases.
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The aim of the study was to evaluate the diagnostic potential of galactose-based microbubble suspension (Levovist) in patients with acute cerebrovascular disease and inadequate transtemporal acoustic window, when examined by transcranial Doppler (TCD). We studied 10 patients with either transient
The G Protein-Coupled Receptor GPR17: Overview and Update.
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The GPR17 receptor is a G protein-coupled receptor (GPCR) that seems to respond to two unrelated families of endogenous ligands: nucleotide sugars (UDP, UDP-galactose, and UDP-glucose) and cysteinyl leukotrienes (LTD4 , LTC4 , and LTE4 ), with significant affinity at micromolar and nanomolar
Structure-activity relationships of an aminosugar cardiac glycoside, ASI-222 HCl, in the heart-lung preparation of the dog.
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ASI-222 [3-beta-O-(4-amino-4,6-dideoxy-beta-D-galactopyranosyl) digitoxigenin HCl] is a semisynthetic aminosugar cardiac glycoside that has been shown to have a greater therapeutic index than ouabain or digoxin in dogs. We have compared the effects of ASI, digitoxigenin,
Chronic ethanol consumption decreases serum sulfatide levels by suppressing hepatic cerebroside sulfotransferase expression in mice.
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Epidemiological studies demonstrate a possible relationship between chronic ethanol drinking and thrombotic diseases, such as myocardial infarction and stroke. However, the precise mechanism for this association remains unclear. Sulfatides are endogenous glycosphingolipids composed of ceramide,
Intracranial collateral pathways assessed by contrast-enhanced three-dimensional transcranial color-coded sonography.
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Individual parameter settings of the duplex machine and limited insonation angles may influence the visualization of small intracranial vessels in 2-D transcranial color-coded sonography. The aim of our study was the morphologic assessment of intracranial collateral pathways (first auditory area
High cardiac output of advanced liver disease persists after orthotopic liver transplantation.
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This study measured cardiac output before and 1 or 2 yr after orthotopic liver transplantation in 23 patients. Cardiac output was measured by thermodilution before transplantation and by first-pass radionuclide angiocardiography at follow-up. Study patients were selected as those doing well
Right-to-left shunt assessed by contrast transcranial Doppler sonography: new insights.
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OBJECTIVE
Simple diagnostic techniques such as contrast transcranial Doppler sonography (cTCDS) are popular for assessing a right-to-left shunt (RLS) because of their high sensitivity. In this study, we applied cTCDS to a large patient group with a patent foramen ovale, proved by contrast
Continuous monitoring of middle cerebral artery recanalization with transcranial color-coded sonography and Levovist.
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OBJECTIVE
Treatment of acute ischemic stroke with intravenous recombinant tissue plasminogen activator (rtPA) is relatively ineffective in patients with large vessel occlusion. Numerous experimental studies have demonstrated that ultrasound (US) can accelerate enzymatic fibrinolysis and acceleration
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