luteolin/диарея

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Selection of Luteolin as a potential antagonist from molecular docking analysis of EGFR mutant.

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The life-threatening sides effect of the current EGFR mutant inhibitors (drugs) such as the eruption of rash which can be seen on the face, chest, back and even the trunk, diarrhea, nausea, vomiting, anorexia and stomatitis, necessitates the discovery of new potent and safe compounds as a

Exacerbation of diclofenac-induced gastroenterohepatic damage by concomitant exposure to sodium fluoride in rats: protective role of luteolin

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NSAID-induced gastrointestinal toxicity is associated with non-selective inhibition of cyclooxygenase (COX)-mediated synthesis of prostaglandins. Fluoride salts, known to stimulate COX-2 synthesis, have also been associated with gastrointestinal damage. The effects of fluoride treatment on NSAID

Luteolin prevents irinotecan-induced intestinal mucositis in mice through antioxidant and anti-inflammatory properties.

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Intestinal mucositis refers to mucosal damage caused by cancer treatment and irinotecan is one of the agents most associated with this condition. Focusing on the development of alternatives to prevent this important adverse effect, we evaluated the activity of the flavonoid luteolin,

Antiviral activity of quercetin 7-rhamnoside against porcine epidemic diarrhea virus.

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Porcine epidemic diarrhea virus (PEDV) is the predominant cause of severe entero-pathogenic diarrhea in swine. The lack of effective therapeutical treatment underlines the importance of research for new antivirals. In this study, we identified Q7R, which actively inhibited PEDV replication with a

Phytochemistry and Ethnopharmacology of Medicinal Plants Used on Safeen Mountain in the Kurdistan Region of Iraq.

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In remote villages of Kurdistan-Iraq, such as in those on Safeen Mountain, decoctions, potions, and oils from the local herbal tradition have provided the only medicinal remedies for centuries, up to today. A variety of diseases are treated with different plant preparations, ranging from simple

High resolution UPLC-PDA-QTOF-ESI-MS/MS analysis of the flavonoid-rich fraction of Lasianthera africana leaves, and in vivo evaluation of its renal and cardiac function effects

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Lasianthera africana P. Beauv. (Icacinaceae) is a traditional Nigerian medicinal plant used for treatment of ulcers, diarrhea, parasitic infections and diabetes. This study was aimed at characterizing the bioactive principles extractable from the flavonoid-rich fraction of L. africana

Suppressive effects of Vochysia divergens aqueous leaf extract and its 5-methoxyflavone on murine macrophages and lymphocytes.

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BACKGROUND Vochysia divergens Pohl (Vochysiaceae), popularly known as "Cambará", is a tree that is resistant to the seasonal floods in the Pantanal, and usually found in monodominant stands called "Cambarazal". The inhabitants of the Pantanal exploit this tree for medicinal uses. Infusions and

In vitro anthelmintic effect of Vicia pannonica var. purpurascens on trichostrongylosis in sheep.

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Vicia species are used for the treatment of malaria, diarrhea, hemorrhoids, kidney problems and infertility in Turkish traditional medicine. The present study was carried out to evaluate the in vitro anthelmintic effects of Vicia pannonica Crantz. var. purpurascens (DC). Ser. extracts. Larval

Fenugreek

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Fenugreek (Trigonella foenum-graecum) seeds contain mucilage, trigonelline, 4-hydroxyisoleucine, sotolon, diosgenin, luteolin, phenolic acids, and protodioscin. Fenugreek has been used in a number of geographical regions worldwide as a galactogogue to increase milk supply and is included in numerous

Effect of two artichoke extracts (36_U and 36_EB) on rat ileum (with respect to bowel syndrome) and the peristaltic threshold.

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The diagnosis and treatment of irritable bowel syndrome (IBS) are complicated. Artichoke extracts are well known to be helpful in various gastrointestinal disorders. A hydrophilic extract 36_U mainly containing luteolin-7-glycoside, luteolin-7-O-glucoside, small amounts of cynarin and luteolin

An evaluation of the inhibitory effects against rotavirus infection of edible plant extracts.

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BACKGROUND Rotaviruses are the single most important cause of severe diarrhea in young children worldwide. The developments of specific, potent and accessible antiviral treatments that restrain rotavirus infection remain important to control rotavirus disease. METHODS 150 plant extracts with

Cocoa-related flavonoids inhibit CFTR-mediated chloride transport across T84 human colon epithelia.

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Cocoa beans have historically been used as a treatment for diarrhea, leading us to hypothesize that polyphenols contained in cocoa inhibit intestinal Cl- secretion. In this study, the dose-dependent effects of flavonoid compounds present in cocoa, or molecularly closely related compounds, were

The assessment of biological activities associated with the major constituents of the methanol extract of 'wild carrot' (Daucus carota L) seeds.

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Daucus carota L. (Family: Apiaceae alt. Umbelliferae), commonly known as 'wild carrot' or 'Queen Anne's-lace,' is an ecologically invasive erect biennial naturalized to Scotland. The ethnobotanical uses of this species include applications in the treatment of cough, diarrhea, dysentery, cancer,

In vivo antitumor effect, induction of apoptosis and safety of Remirea maritima Aubl. (Cyperaceae) extracts.

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BACKGROUND Remirea maritima has been widely used in the treatment of diarrhea, kidney disease, and high fever and for therapeutic purposes, such as an analgesic and anti-inflammatory. However, few scientific research studies on its medicinal properties have been reported. OBJECTIVE The present study

Chemical and biological characterisation of Machaerium hirtum (Vell.) Stellfeld: absence of cytotoxicity and mutagenicity and possible chemopreventive potential.

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Machaerium hirtum (Vell.) Stellfeld (M.hirtum) is a plant known as 'jacarandá-bico-de-pato' whose bark is commonly used against diarrhea, cough and cancer. The aim of this study was to phytochemically characterise the hydroethanolic extract of this plant, investigate its antimutagenic activities

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