oligospermia/ожирение

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Obesity and increased risk for oligozoospermia and azoospermia.

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The Association Between Race, Obesity, and Sperm Quality Among Men Attending a University Physician Practice in Washington, DC

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A decades-long decline in sperm counts in Western countries has coincided with an increase in obesity rates, prompting study into their association. Few of these studies have incorporated men of color, the sperm health of whom is relatively unknown. The present exploratory study evaluated the

Specific prolactin release refractoriness to thyroid-stimulating hormone-releasing factor in an obese infertile man.

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A specific PRL unresponsiveness to TSH-releasing factor was uncovered during the workup of an obese man with infertility due to oligozoospermia. Normal PRL responses were demonstrated in response to insulin-induced hypoglycemia, MTC, and sleep. Borderline-low circulating T without elevated baseline

Relation between male obesity and male infertility in a Tunisian population.

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Obesity is associated with significant disturbance in the hormonal milieu that can affect the reproductive system. Male infertility affects approximately 6% of reproductive-aged men. It has been suggested that overweight men or men with obese body mass index (BMI) experience prolonged time to

Association of aromatase (TTTAn) repeat polymorphism length and the relationship between obesity and decreased sperm concentration.

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BACKGROUND Obesity in men is associated with low sperm count, however, this finding is inconsistent. Here, we describe length of the short tandem repeat aromatase (CYP19A1) polymorphism and its relationship to increased weight and sperm count. METHODS A cohort of 215 men was recruited from the

Male Obesity Associated Gonadal Dysfunction and the Role of Bariatric Surgery

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Obesity is an ever growing pandemic and a prevalent problem among men of reproductive age that can both cause and exacerbate male-factor infertility by means of endocrine abnormalities, associated comorbidities, and direct effects on the precision and throughput of spermatogenesis. Robust

Association between obesity and sperm quality.

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There is awareness of likelihood of abnormal spermatozoa in obese men; however, results from previous studies are inconclusive. Advances in computer-aided sperm analysis (CASA) enable precise evaluation of sperm quality and include assessment of several parameters. We studied a retrospective cohort

Twenty-four-hour monitoring of scrotal temperature in obese men and men with a varicocele as a mirror of spermatogenic function.

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OBJECTIVE How do day and night scrotal temperatures, spermatogenesis parameters, sex hormones and intratesticular perfusion in obese men and men with a varicocele compare with healthy controls? CONCLUSIONS Compared with healthy controls, 24-h monitoring of scrotal temperature in men with a

How effective are weight-loss interventions for improving fertility in women and men who are overweight or obese? A systematic review and meta-analysis of the evidence.

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The prevalence of obesity is increasing worldwide, with a corresponding increase in overweight and obese patients referred with infertility. This systematic review aimed to determine whether non-surgical weight reduction strategies result in an improvement in reproductive parameters affected by

Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity.

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Hormone-sensitive lipase (HSL) is known to mediate the hydrolysis not only of triacylglycerol stored in adipose tissue but also of cholesterol esters in the adrenals, ovaries, testes, and macrophages. To elucidate its precise role in the development of obesity and steroidogenesis, we generated HSL

The role of leptin and obesity on male infertility.

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Several studies suggest a strong association between leptin, obesity, and infertility with respect to the hypothalamic-pituitary-gonadal (HPG) axis, androgen regulation, and sperm production, but the direct mechanistic association between these is still largely unexplored. This review

Male obesity and alteration in sperm parameters.

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OBJECTIVE To study the effect of male obesity on sperm parameters and erectile dysfunction. METHODS Retrospective analysis. METHODS Referral fertility center. METHODS Couples presenting for infertility treatment. METHODS On presentation, all men reported their weight and height and filled out an

Muscular dystrophies at different ages: metabolic and endocrine alterations.

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Common metabolic and endocrine alterations exist across a wide range of muscular dystrophies. Skeletal muscle plays an important role in glucose metabolism and is a major participant in different signaling pathways. Therefore, its damage may lead to different metabolic disruptions. Two of the most

Aromatase inhibitors in male sex.

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Aromatase inhibitors (AI) have been used in males in idiopathic short stature, constitutional delay of puberty, precocious puberty, gynecomastia, oligospermia, hypogonadism related to obesity and ageing. This retrospective study echoed the benefit of AI in Indian males in varied conditions.

Effect of lipid metabolism on male fertility.

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Cholesterol and lipid homeostasis is important for male fecundity. However, the plasma total cholesterol level does not reflect sperm concentration and motility. Adipose tissue in mammals is the main tissue contributing to the dynamic equilibrium of lipid synthesis and catabolism. However, recent

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