The Effect of Bariatric Surgery to Central Sensitization

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Postavenie

Sponzori

Bursa Yüksek İhtisas Education and Research Hospital

KLINICKÁ ŠTÚDIA: NCT03460691

BioSeek: nct03460691

Kľúčové slová

Abstrakt

Nowadays obesity is emerging as a very common health problem. It has been shown in various studies that obesity may be an important risk factor for the onset and progression of knee osteoarthritis (OA). The aim of this study is to determine the effects of bariatric surgery on knee pain, loss of function, quality of life and central sensitization.

Popis

Weight loss in patients with knee OA reduces pain and provides functional improvement. It has been shown that bariatric surgery combined with diet and exercise changes have positive effects on weight loss, knee pain and function.

Neuropathic pain is a disease that affects the somatosensory system or pain that results in a lesion. It has been reported that neuropathic pain is more frequently seen in patients with high body mass index.

The hyperreactivity of the central nervous system (CNS) plays an important role in the chronic pain of OA patients. It has been shown that CNS becomes hypersensitive in people with chronic OA pain and central sensitization phenomenon plays an important role in pain complaints reported by these patients.

The aim of this study is to determine the effects of bariatric surgery on knee pain, loss of function, quality of life and central sensitization.

Termíny

Naposledy overené:	02/28/2018
Prvý príspevok:	03/01/2018
Odhadovaná registrácia bola odoslaná:	03/07/2018
Prvý príspevok:	03/08/2018
Posledná aktualizácia bola odoslaná:	03/07/2018
Posledná aktualizácia bola zverejnená:	03/08/2018
Aktuálny dátum začatia štúdie:	03/08/2018
Odhadovaný dátum dokončenia primárneho okruhu:	12/08/2018
Odhadovaný dátum dokončenia štúdie:	12/08/2018

Stav alebo choroba

Bariatric Surgery

Central Sensitization

Intervencia / liečba

Procedure: Group 1

Fáza

Skupiny zbraní

Arm	Intervencia / liečba
Group 1 Group 1:patients who will undergo the bariatric surgery	Procedure: Group 1 Bariatric surgery will done to the patients who were morbid obesity

Kritériá oprávnenosti

Vek vhodný na štúdium	18 Years To 18 Years
Pohlavia vhodné na štúdium	All
Metóda vzorkovania	Probability Sample
Prijíma zdravých dobrovoľníkov	Áno
Kritériá	Inclusion Criteria: - Patients decided to undergo bariatric surgery - Patients with knee pain more than 3 months. Exclusion Criteria: - Patients with mental impairment, - Patients with inflammatory rheumatic disease, - Patients who had previously undergone knee surgery

Výsledok

Primárne výstupné opatrenia

1. numeric rating scale (NRS) [6 months]

It is commonly used to measure the severity of the patients' pain. It consists of a line 10 cm. long and marked with numbers from 0 to 10. The patient is asked to mark the point corresponding to the severity of the pain on this line in the range from 0 (no pain) to 10 (most severe pain).

2. Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC) [6 months]

for function

3. Nottingham Health Profile [6 months]

for quality of life

4. Central Sensitization Inventory (CSI) [6 months]

for central sensitization

The Effect of Bariatric Surgery to Central Sensitization

Kľúčové slová

chronic pain

osteoarthritis

neuralgia

obezita

strata váhy