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dental plaque/prolín
Odkaz sa uloží do schránky
Strana 1 od 24 výsledky
Enzymic properties of human dental plaque proline iminopeptidases adsorbed on hydroxylapatite.
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Agglutinin and acidic proline-rich protein receptor patterns may modulate bacterial adherence and colonization on tooth surfaces.
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Bacterial binding to salivary proteins may in part account for individual differences in the colonization of tooth surfaces. High-molecular-weight glycoproteins, agglutinins, mediate S. mutans adherence, whereas acidic proline-rich proteins mediate adherence of other early-colonizing streptococci
Abiotrophia defectiva adhere to saliva-coated hydroxyapatite beads via interactions between salivary proline-rich-proteins and bacterial glycerlaldehyde-3-phosphate dehydrogenase
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Abiotrophia defectiva is a species of nutritionally variant streptococci that is found in human saliva and dental plaques and that has been associated with infective endocarditis. In our previous study, we found that A. defectiva could bind specifically to saliva-coated hydroxyapatite beads (SHA).
Possible release of an ArgGlyArgProGln pentapeptide with innate immunity properties from acidic proline-rich proteins by proteolytic activity in commensal streptococcus and actinomyces species.
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This study suggests degradation of salivary acidic proline-rich proteins (PRPs) into potential innate-immunity-like peptides by oral Streptococcus and Actinomyces species. PRP degradation paralleled cleavage of Pro-containing substrates. PRP degradation by S. gordonii strain SK12 instantly released
Stickland reactions of dental plaque.
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Dental plaque samples from monkeys (Macaca fascicularis) were shown to contain proline reduction activity in coupled Stickland reactions with other amino acids and also with certain end products of bacterial glucose metabolism. The unusually high concentration of bound and free proline in the oral
Differential Utilization of Basic Proline-Rich Glycoproteins during Growth of Oral Bacteria in Saliva.
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Although saliva is widely recognized as a primary source of carbon and nitrogen for growth of the dental plaque biofilm community, little is known about how different oral bacteria utilize specific salivary components. To address this question, 32 strains representing 16 genera commonly isolated
Distinct signatures of dental plaque metabolic byproducts dictated by periodontal inflammatory status.
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Onset of chronic periodontitis is associated with an aberrant polymicrobial community, termed dysbiosis. Findings regarding its etiology obtained using high-throughput sequencing technique suggested that dysbiosis holds a conserved metabolic signature as an emergent property. The purpose of this
Human dental plaque pH, and the organic acid and free amino acid profiles in plaque fluid, after sucrose rinsing.
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The relationship between these factors was studied in plaque and plaque fluid samples taken at intervals during the Stephan pH curve following a sucrose mouth rinse. Levels of lactate rose after the rinse, then fell during the pH recovery phase. Levels of acetate, propionate and phosphate fell after
The free amino acids in human dental plaque.
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Analysis of plaques from maxillary and mandibular incisors for free amino acids showed that the dicarboxylic amino acids, glutamic and aspartic, were present in largest amounts, with glutamic acid comprising at least 50 per cent of the total pool. Other amino acids in decreasing order of prominence
Disulfide Bonds: A Key Modification in Bacterial Extracytoplasmic Proteins.
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Disulfide bonds are a common posttranslational modification that contributes to the folding and stability of extracytoplasmic proteins. Almost all organisms, from eukaryotes to prokaryotes, have evolved enzymes to make and break these bonds. Accurate and efficient disulfide bond formation can be
Bacterial degradation of immunoglobulin A1 in relation to periodontal diseases.
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Periodontal diseases affect millions of people world wide. Prevention and treatment of these diseases require considerable attention from the individual as well as society and cause great expenses. Understanding disease etiology and mechanisms of pathogenesis is a prerequisite for optimal treatment
Role of cryptic receptors (cryptitopes) in bacterial adhesion to oral surfaces.
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Progress in characterizing the receptors that promote bacterial attachment to teeth and oral epithelial cells has suggested that hidden molecular segments may frequently be involved. Such cryptic receptors, referred to as 'cryptitopes', may become exposed by several mechanisms. Hidden segments of
Characterization of low-molecular-weight peptides in human parotid saliva.
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The low-molecular-weight components of human saliva remain poorly characterized. Therefore, low-molecular-weight peptides (Mr < 3000) have been purified from human parotid saliva and characterized with respect to their amino acid sequence. From the sequences obtained, it is likely that these
Use of a replica-plate assay for the rapid assessment of salivary protein-bacteria interactions.
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A replica-plate assay was used to screen for the interaction of salivary molecules with dental plaque bacteria. Bacterial colonies cultured from supragingival plaque on sheep-blood (SB) agar were replica-plated onto nitrocellulose membranes overlaying SB or mitis-salivarius agar. Membranes with
Interaction of parotid saliva basic glycoprotein with Streptococcus sanguis ATCC 10557.
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It is postulated that an initial step in dental plaque formation is the adherence of oral bacteria to the salivary pellicle. Recently, we have found that a proline-rich and basic glycoprotein (MGP) from human parotid saliva, which is successfully purified by Concanavalin A-Sepharose affinity
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