3 výsledky
A pilot trial with 2 sheep per group demonstrated that no protection is provided by cysteine, sulphur or sodium thiosulphate, when administered simultaneously with daily doses of Geigeria filifolia plant material. Treatment with piracetam of 4 sheep showing symptoms of vermeersiekte did not improve
The sesquiterpene lactones isolated from Geigeria were found to be incapable of inducing rat peritoneal mast cell degranulation at levels of 0.3-1.6 mM. The sulphydryl reagent, N-ethylmaleimide, too was unable to trigger mast cell secretion. Instead, it was observed that these compounds inhibited
Certain species of Geigeria contain sesquiterpene lactones which cause vomiting disease in sheep. Dihydrogriesenin (DHG), a sesquiterpene lactone from G. asperta, contains an alpha-methylene function which can spontaneously react with thiol groups on proteins to form a covalent adduct. A specific