4 výsledky
We investigated the composition of extracts derived from Guaiacum spp. (Zygophyllaceae), a group of neotropical tree species with varied uses in Central and South American traditional medicine. Activity-guided fractionation of Guaiacum heartwood extracts led to the identification of four new
OBJECTIVE
The objective of this study was to evaluate the cytotoxic and anticancer activities of extracts from 7-species of endemic and native plants from Puerto Rico.
METHODS
The plant species selected for this study were Canella winterana, Croton discolor, Goetzea elegans, Guaiacum officinale,
The lipoxygenase inhibitor nordihydroguaiaretic acid, a natural product purified from Larrea divaricata and Guaiacum officinale, showed a marked capacity to induce differentiation of various human malignant tumor cell lines. Nordy, a derivative of nordihydroguaiaretic acid, has been shown to