intestinal volvulus/arginín

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Molecular characterization and expression of Onchocerca volvulus glutathione reductase.

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Glutathione metabolism represents a potential target for anti-parasite drug design. The central role of glutathione reductase (GR) in maintenance of the thiol redox state and in anti-oxidative defence has to be evaluated in more detail in order to establish the essential function of this enzyme for

Cloning and biochemical characterization of blisterase, a subtilisin-like convertase from the filarial parasite, Onchocerca volvulus.

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Blisterase is a subtilisin-like proprotein convertase of nematodes. The enzyme is named after the blistered cuticle found in Caenorhabditis elegans with the bli-4 e937 mutation. The critical role of the enzyme in cuticle production makes it a potential drug target for parasitic nematodes. We have

Arginine in liquid contents of displaced abomasal in dairy cows.

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Increased nitric oxide synthesis by abomasal neurons was related to disorders of abomasal muscle function in displaced abomasum in a previous study. Nitric oxide is synthesised from L-arginine. The objectives of the studies reported on here were to isolate factors associated with arginine in

O-Crystallin, arginine kinase and ferritin from the octopus lens.

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Three proteins have been identified in the eye lens of the octopus, Octopus dofleini. A 22 kDa protein comprising 3-5% of the soluble protein of the lens is 35-43% identical to a family of phosphatidylethanolamine-binding proteins of vertebrates. Other members of this family include the

Onchocerca volvulus: identification and characterization of an immunogenic eggshell protein (Oveg1).

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A major antigen recognized by human sera in Onchocerca volvulus infections is a parasite eggshell protein. The cDNA clone for this antigen was isolated from a lambda gt11 O. volvulus cDNA library using antisera from patients with high microfilarial counts. Sequence analysis of the cDNA clone

Role of endothelium and nitric oxide in the in vitro response of equine colonic venous rings to vasoconstrictor agents.

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OBJECTIVE To determine in vitro contractile responses of equine colonic veins to various vasoconstrictor agents. METHODS Colonic veins collected from 8 adult horses. METHODS Veins were cut into 4-mm-wide rings, placed in organ baths at 37 C, and attached to a force-transducer interfaced with a

Polyamine metabolism in filarial worms.

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The human and animal filarial parasites Onchocerca volvulus, Dirofilaria immitis, Brugia patei and Litomosoides carinii contained low levels of putrescine but much higher levels of spermidine and spermine as estimated by ion-pair high pressure liquid chromatography; N-acetylated polyamines were

In vitro responses of equine colonic arterial and venous rings to adenosine triphosphate.

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OBJECTIVE To evaluate the in vitro effects of adenosine tryphosphate (ATP) on vasomotor tone of equine colonic vasculature. METHODS Arteries and veins from the left ventral colon of 14 mixed-breed horses euthanatized for reasons unrelated to cardiovascular or gastrointestinal tract

Results of growth trophic therapy in children with short bowel syndrome.

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OBJECTIVE In addition to the structural, ultrastructural, and functional changes that occur after extensive enterectomy or in utero bowel loss that results in short bowel syndrome (SBS), a complex array of humoral responses take place that may also affect adaptation of the remaining small intestine

Fc gamma RIIa (CD32) polymorphism and onchocercal skin disease: implications for the development of severe reactive onchodermatitis (ROD).

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The pathologic manifestations of Onchocerca volvulus infection depend on the interplay between the host and the parasite. A genetic single nucleotide polymorphism in the Fc gamma RIIa gene, resulting in arginine (R) or histidine (H) at position 131, affects the binding to the different IgG

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