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A Serosurvey Identifying Vulnerability to Measles in Health Care Workers. A Hospital-Based Prospective Seroprevalence Study

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The aim of this serological survey was to assess the persistence of measles antibodies among health care workers (HCWs) at risk of incidental measles. A prospective study of measles-specific antibodies in serum samples obtained from a total of 2782 participants aged 19-89 years was conducted between

[Viruses and the neuroendocrine system: model of murine obesity induced by cerebral infection by canine distemper virus].

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It is currently well established that the nervous, endocrine and immune systems inter-communicate using biologically active soluble factors, synthesised and produced by these three systems themselves (e.g. immunomodulator effect of hormones, effect of substances secreted by immune cells on endocrine

Severe Measles Infection: The Spectrum of Disease in 36 Critically Ill Adult Patients.

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France has recently witnessed a nationwide outbreak of measles. Data on severe forms of measles in adults are lacking. We sought to describe the epidemiologic, clinical, treatment, and prognostic aspects of the disease in adult patients who required admission to an intensive care unit (ICU). We

Effect of second dose of measles vaccine on measles antibody status: a randomized controlled trial.

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OBJECTIVE To evaluate the effect of the second dose of measles vaccine on measles antibody status during childhood. METHODS Immunization centre of Under-five Clinic of the Department of Community Medicine at a tertiary-hospital. METHODS Randomized Controlled trial. METHODS Children from 6 years to

Specific alteration of the expression of selected hypothalamic neuropeptides during acute and late mouse brain infection using a morbillivirus: relevance to the late-onset obesity?

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Neurotropic viruses are involved in pathologies of the central nervous system, triggering transient or irreversible disorders, such as neurological diseases or homeostasis imbalance. In experimental animals, viruses have been shown to cause obesity, a complex disease depending on multiple factors,

Severe measles in a young female patient with chronic, generalized Trichophyton rubrum infection showing type 2 helper T cell-dominant immunologic reactivity.

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An obese 18-year-old girl without a history of atopic dermatitis or a systemic immunosuppressive disorder had severe measles with liver dysfunction and pneumonia. For the previous 3 years she had had a chronic untreated generalized Trichophyton rubrum infection. The rash of the measles tended to

Down regulation of melanin concentrating hormone in virally induced obesity.

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Obesity is a complex disease involving genetic components and environmental factors and probably associated with the dysregulation of central homeostasis normally maintained by the hypothalamic neuroendocrine/neurotransmitter network. We previously reported that canine distemper virus (CDV), which

A virally induced obesity syndrome in mice.

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An obesity syndrome was found in a number of mice infected as young adults with canine distemper virus, a morbillivirus antigenically related to measles. Body weights of obese animals 16 to 20 weeks after infection were comparable to those reported for genetically obese mice and for mice rendered

Attenuated measles virus controls pediatric acute B-lineage lymphoblastic leukemia in NOD/SCID mice.

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Novel therapies are needed for pediatric acute lymphoblastic leukemia resistant to conventional therapy. While emerging data suggest leukemias as possible targets of oncolytic attenuated measles virus, it is unknown whether measles virus can eradicate disseminated leukemia, in particular pediatric

Immunisation and type 1 diabetes mellitus: is there a link?

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Recent evidence from animal studies has raised the possibility that immunisation by vaccines can influence the pathogenesis of type I (insulin-dependent) diabetes mellitus. In non-obese diabetic mice and biobreeding rats, complete Freund's adjuvant and bacillus Calmette-Guérin (BCG) vaccine have

[Health habits and vaccination status of Lebanese residents: are future doctors applying the rules of prevention?].

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BACKGROUND There has never been a nationally representative survey of medical students' personal health-related practices, although they are inherently of interest and may affect patient-counseling practices. This study evaluated the health practices and the vaccination status of first year

Adding Natural Areas to Social Indicators of Intra-Urban Health Inequalities among Children: A Case Study from Berlin, Germany.

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Research suggests that there is a relationship between the health of urban populations and the availability of green and water spaces in their daily environment. In this paper, we analyze the potential intra-urban relationships between children's health determinants and outcomes and natural areas in

[Health checkups for children of 3-4 years of age in the Hauts-de-Seine department (France): results and prospects].

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BACKGROUND A mission of the department's State Maternal and Child Welfare Service is to organize the first checkups for children attending nursery schools. Here, we present the data of the Hauts-de-Seine department (France). METHODS All of the PMI physicians who carry out checkups of children aged 3

Enhancing the Teaching of Evolution in Public Health.

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CONCLUSIONS Public health courses are emerging as popular undergraduate offerings, especially at universities with schools of public health. It is important to note that evolution has shaped the burden of disease in the modern world in which we practice and educate for public health. Human cultures

Brain structures selectively targeted by canine distemper virus in a mouse model infection.

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Paramyxoviruses such as measles virus or canine distemper virus are etiological agents for acute and chronic encephalitis (measles inclusion body encephalitis, subacute sclerosing panencephalitis and chronic distemper encephalitis or old dog encephalitis). The mechanisms by which viral injury leads

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