papaverine/atrofia

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Effect of imidazole, papaverine and histamine on learning and memory in albino rats.

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In experiments for learning of albino rats in a maze and testing of the memory 24 hours and 30 days after learning, it was established that: Imidazole introduced i.p. in doses of 10, 30 and 60 mg/kg had no effect on learning, though it improved the memory both after administration 1 to 15 min before

[Efficacy of intracisternal papaverine on symptomatic vasospasm].

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This study reports the effect of intracisternal administration of papaverine in 15 patients with vasospasm due to rupture of aneurysm. All patients had undergone clipping of aneurysm and had neurological deterioration and decreasing level of consciousness. Bolus injection of 40 mg of 1% papaverine

Intraarterial papaverine infusion for cerebral vasospasm after subarachnoid hemorrhage.

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OBJECTIVE To evaluate the techniques and efficacy of intracranial intraarterial papaverine infusion for symptomatic vasospasm after subarachnoid hemorrhage caused by aneurysm rupture. METHODS Papaverine was infused on 19 occasions in 14 patients, 6 hours to 2 days after spasm became apparent

Intraarterial infusion of high-concentration papaverine damages cerebral arteries in rats.

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OBJECTIVE To determine the appropriate concentration of papaverine for therapeutic intraarterial infusion against cerebral vasospasm. METHODS We investigated histopathologic changes in cerebral arteries and brain tissue of normal Wistar rats that had received infusions of papaverine via the carotid

Effectiveness of intra-arterially infused papaverine solutions of various concentrations for the treatment of cerebral vasospasm.

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We evaluated the effect of intra-arterially infused papaverine solutions of various concentrations on cerebral vasospasm following subarachnoid haemorrhage. A total of 90 vascular territories in 46 patients with symptomatic cerebral vasospasm after subarachnoid haemorrhage were treated with

Distribution of intraarterially administered papaverine in endovascular treatment of delayed cerebral vasospasm.

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The distribution of selectively administered papaverine was determined in nine patients with delayed cerebral vasospasm in the territories of the anterior (ACA) and/or middle cerebral arteries (MCA) secondary to aneurysmal subarachnoid hemorrhage by simultaneous infusion with

Neurotoxicity of intra-arterial papaverine preserved with chlorobutanol used for the treatment of cerebral vasospasm after aneurysmal subarachnoid hemorrhage.

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OBJECTIVE Papaverine is used to vasodilate cerebral arteries undergoing vasospasm from subarachnoid hemorrhage. However, papaverine inhibits cellular respiration in vitro and could cause neurotoxicity in humans. METHODS We studied 5 consecutive patients with cerebral vasospasm who were treated with

Intraarterial papaverine as an adjunct to transluminal angioplasty for vasospasm induced by subarachnoid hemorrhage.

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Basilar artery vasospasm refractory to medical therapy was confirmed by clinical deterioration and angiography in a 47-year-old man; successful passage of a nondetachable balloon system and angioplasty were facilitated by intraarterial papaverine.

[Bioelectrical, biochemical and histomorphological changes in the ocular tissues in pituitrin hypertension and the use of euphylline and papaverine].

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Experimental study on rabbits of bioelectric and biochemical characteristics of eye tissues during pituitrin hypertension and application of euphylline and papaverine as well as comparison of the data obtained indicate that during pituitrin hypertension, transtissue potential difference and density

The use of intraarterial papaverine in the management of vasospasm complicating arteriovenous malformation resection. Report of two cases.

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The authors report two cases of treatment by intraarterial papaverine of cerebral vasospasm complicating the resection of an arteriovenous malformation (AVM). Both cases had successful reversal of vasospasm documented on angiography. In the first case sustained neurological improvement occurred,

Papaverine inhibits α-synuclein aggregation by modulating neuroinflammation and matrix metalloproteinase-3 expression in the subacute MPTP/P mouse model of Parkinson's disease

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Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor impairments. Most PD drugs act by improving motor impairments, whereas very few drugs that efficiently recover PD-related neuropathological features, particularly α-synuclein-related toxicity, have been developed. In

[Effectiveness of percutaneous transluminal angioplasty and intra-arterial papaverine infusion for symptomatic vasospasm after subarachnoid hemorrhage].

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OBJECTIVE To evaluate the clinical effectiveness of PTA and/ or intra-arterial infusion of papaverine (PPV) for the treatment of symptomatic vasospasm after subarachnoid hemorrhage. METHODS From September 1989 to March 1996, twenty patients with symptomatic vasospasm were treated by PTA and/or

Stability of the intra-epithelial component of the blood-testis barrier in epinephrine-induced testicular degeneration in Syrian hamsters.

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Adult male Syrian hamsters were given daily intraperitoneal injections of epinephrine (1.0 mg/kg) and papaverine, a vasodilator, (60 mg/kg) for a period of ten days. After the treatment period, lanthanum and horseradish peroxidase tracer studies were used to examine the intra-epithelial component of

Deterioration of endothelial and smooth muscle cell function in DCD kidneys after static cold storage in IGL-1 or UW.

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BACKGROUND Kidneys obtained from donors after cardiac death are damaged by the combination of warm and cold ischemia. Although the parenchymal damage of these kidneys is well studied, little is known about the functional effects of warm and cold ischemia on the renal vascular bed. We compared kidney

Treating erectile dysfunction in renal transplant recipients.

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Erectile dysfunction is common in male kidney transplant recipients. Interference with the physiology of erections can be attributed to recipient co-morbidities, the renal transplant operation, medication adverse effects, relationship problems and changes in mental health. A treatment-oriented

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