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piperidine/seizures
Odkaz sa uloží do schránky
Strana 1 od 18 výsledky
Dimeric piperidine, tetrahydropyridine and piperazine derivatives
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Prihlásiť Registrácia
The present invention relates to a novel class of dimeric piperidine, 1,2,3,6-tetrahydropyridine and piperazine derivatives in which the nitrogen atoms of the six-membered basic rings are linked together via a spacer chain to form a symmetrical dimeric bis(1-piperidyl),
Dimeric piperidine, tetrahydropyridine and piperazine derivatives
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Prihlásiť Registrácia
The present invention relates to a novel class of dimeric piperidine, 1,2,3,6-tetrahydropyridine and piperazine derivatives in which the nitrogen atoms of the six-membered basic rings are linked together via a spacer chain to form a symmetrical dimeric bis(1-piperidyl),
Dimeric piperidine, tetrahydropyridine and piperazine derivatives
Články môžu prekladať iba registrovaní používatelia
Prihlásiť Registrácia
The present invention relates to a novel class of dimeric piperidine, 1,2,3,6-tetrahydropyridine and piperazine derivatives in which the nitrogen atoms of the six-membered basic rings are linked together via a spacer chain to form a symmetrical dimeric bis(1-piperidyl),
Dimeric piperidine, tetrahydropyridine and piperazine derivatives
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Prihlásiť Registrácia
The present invention relates to a novel class of dimeric piperidine, 1,2,3,6-tetrahydropyridine and piperazine derivatives in which the nitrogen atoms of the six-membered basic rings are linked together via a spacer chain to form a symmetrical dimeric bis(1-piperidyl),
4-substituted piperidine analogs and their use as subtype selective NMDA receptor antagonists
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention is related to 4-substituted piperidine analogs, including hydroxypiperidine and tetrahydropyridine analogs, as well as novel intermediates of the 4-substituted analogs. The analogs are selectively active as antagonists of
4-substituted piperidine analogs and their use as subtype selective NMDA receptor antagonists
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Prihlásiť Registrácia
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention is related to 4-substituted piperidine analogs, including hydroxypiperidine and tetrahydropyridine analogs, as well as novel intermediates of the 4-substituted analogs. The analogs are selectively active as antagonists of
2-substituted piperidine analogs and their use as subtype-selective NMDA receptor antagonists
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention is related to 2-substituted piperidine analogs. The analogs are selectively active as antagonists of N-methyl-D-aspartate (NMDA) receptor subtypes. The invention is also directed to the use of 2-substituted piperidine analogs as
2-substituted piperidine analogs and their use as subtype-selective NMDA receptor antagonists
Články môžu prekladať iba registrovaní používatelia
Prihlásiť Registrácia
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention is related to 2-substituted piperidine analogs. The analogs are selectively active as antagonists of N-methyl-D-aspartate (NMDA) receptor subtypes. The invention is also directed to the use of 2-substituted piperidine analogs as
4-substituted piperidine analogs and their use as subtype selective NMDA receptor antagonists
Články môžu prekladať iba registrovaní používatelia
Prihlásiť Registrácia
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention is related to 4-substituted piperidine analogs, including hydroxypiperidine and tetrahydropyridine analogs. The analogs are selectively active as antagonists of N-methyl-D-aspartate (NMDA) receptor subtypes. The invention is also
Piperidine derivatives as subtype selective N-Methyl-D-Aspartate antagonists
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FIELD OF INVENTION
The invention relates to piperidine derivatives as N-Methyl-D-Aspartate (NMDA) antagonists useful in the treatment of diseases and disorders responsive to antagonism of NMDA receptors.
BACKGROUND OF THE INVENTION
Many of the physiological and pathophysiological effects of the
Dimeric piperidine, tetrahydropyridine and piperazine derivatives
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This is a continuation of international application Ser. No. PCT/DK93/00198, filed Jun. 9, 1993 published as WO93/25527, Dec. 23, 1993.
The present invention relates to a novel class of dimeric piperidine, 1,2,3,6-tetrahydropyridine and piperazine derivatives in which the nitrogen atoms of the
4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide
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FIELD OF THE INVENTION
The present invention relates to 4-hydroxy-4-methyl-piperidine-1-carboxylic acid(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide, which is a compound of formula
##STR00002## and to pharmaceutically acceptable acid addition salts thereof. This compound is generically
Piperidine derivatives having anxiolytic effect
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This is a continuation of international application Ser. No. PCT/DK92/00183, filed Jun. 12, 1992.
The present invention relates to a class of piperidine compounds having anxiolytic effect and potently binding to the sigma receptors and therefore being useful in the treatment of psychic and
Piperidine derivatives having anxiolytic effect
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The present invention relates to a class of piperidine compounds having anxiolytic effect, and potently binding to the sigma receptors and therefore being useful in the treatment of psychic and neurologic disorders.
Various related compounds are known from the prior art.
So, U.S. Pat. Nos. 3,686,186
Piperidine derivates having anxiolytic effect
Články môžu prekladať iba registrovaní používatelia
Prihlásiť Registrácia
The present invention relates to a class of piperidine compounds having anxiolytic effect and potently binding to the sigma receptors and therefore being useful in the treatment of psychic and neurologic disorders.
Various related compounds are known from the prior art.
So, U.S. Pat. Nos. 3,686,186
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