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pneumoperitoneum/hypoxia

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Strana 1 od 74 výsledky

Pathogenesis of CO(2) pneumoperitoneum-induced metabolic hypoxemia in a rabbit model.

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OBJECTIVE To investigate the effects of carbon dioxide (CO(2)) pneumoperitoneum-induced changes in blood gases, acid-base balance, and oxygen homeostasis in rabbits. METHODS Prospective, randomized, controlled study (Canadian Task Force classification I). METHODS University training and teaching

[Effects of hypoxia-inducible factor-1α on human gastric cancer cell apoptosis under in vitro CO(2) pneumoperitoneum environment].

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OBJECTIVE To study the effect of hypoxia-inducible factor-1α (HIF-1α) on human gastric cancer cells apoptosis in simulated CO2 pneumoperitoneum environment. METHODS Applied closed box to simulated CO2 pneumoperitoneum environment under the pressure of 0, 5, 10 and 15 mm Hg (1 mm Hg = 0.133 kPa).
OBJECTIVE To investigate the effects of hypoxia-inducible factor (HIF) inhibitors, flotation agents, barriers, and a surfactant on pneumoperitoneum-enhanced adhesions in a laparoscopic mouse model. METHODS Prospective randomized trial (Canadian Task Force classification I). METHODS Department of

Peritoneal mesothelial hypoxia during pneumoperitoneum is a cofactor in adhesion formation in a laparoscopic mouse model.

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OBJECTIVE To develop a laparoscopic mouse model to evaluate the hypothesis that mesothelial hypoxia during pneumoperitoneum is a cofactor in adhesion formation. METHODS Prospective randomized trials. METHODS Academic research center. METHODS One hundred thirty female Naval Medical Research Institute
OBJECTIVE To evaluate the role of hypoxia inducible factors (HIFs) 1alpha and 2alpha in adhesion formation after laparoscopic surgery. METHODS Prospective, randomized study. METHODS Academic research center. METHODS Forty Swiss/129SvJ wild-type mice and transgenic mice partially deficient for the
BACKGROUND Animal experiments have suggested that the laparoscopic peritoneal environment is hypoxic. This study aimed to investigate whether peritoneal tissue is hypoxic on a cellular level during a carbon dioxide (CO(2)) pneumoperitoneum at different intraperitoneal pressures (IPPs) and to
Although symptomatic carbon dioxide (CO(2)) embolism is rare, it recognized as a potentially fatal complication of laparoscopic surgery. Sudden hemodynamic instability could be a CO(2) embolism especially during insufflation. A 65-year-old man received laparoscopic prostatectomy for 5 hours under

Tension pneumoperitoneum in a child resulting from high-frequency oscillatory ventilation: a case report and review of the literature.

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An 18-month-old male infant was placed on high-frequency oscillatory ventilation for profound hypoxemia and subsequently developed tension pneumoperitoneum. He underwent a bedside exploratory laparotomy for suspected perforated viscus. No intestinal perforation was identified, and a diagnosis of
We reported a case with tension pneumoperitoneum while being on high-frequency oscillatory ventilation.A 12-month-old Thai girl presented with acute respiratory distress syndrome, septic shock, and bacterial pneumonia. Although supported with mechanical

Effect of pneumoperitoneum on renal tissue oxygenation and blood flow in a rat model.

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OBJECTIVE To determine the correlation between the renal blood flow (RBF) and tissue oxygenation (PO(2)) at varying intra-abdominal pressures (IAPs) and to compare the effects on renal blood flow from carbon dioxide-induced pneumoperitoneum. METHODS Carbon dioxide pneumoperitoneum was established in

The influence of the CO₂ pneumoperitoneum on a rat model of intestinal anastomosis healing.

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BACKGROUND The CO(2) pneumoperitoneum, which is used for laparoscopic surgery, causes local and systemic effects in patients. Concern arises about what the pressurized anoxic environment of the CO(2) pneumoperitoneum has on intestinal healing. Earlier experimental work showed a negative correlation

Marked pneumoperitoneum 3 weeks after percutaneous endoscopic gastrostomy.

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In November 2001, a 29-year-old woman was admitted to the hospital because of dysphagia due to an apallic state caused by cerebral anoxia. Nutritional support was maintained by nasogastric tube feeding for approximately 3 months. For improvement of the body state maintenance and quality of life, a
BACKGROUND Previous animal studies suggested that the peritoneal environment during a carbon dioxide (CO(2)) pneumoperitoneum is hypoxic and that this may contribute to the formation of intra-abdominal adhesions or the growth of malignant cells. There is no study, however, that investigates the

Maternal insufflation during the second trimester equivalent produces hypercapnia, acidosis, and prolonged hypoxia in fetal sheep.

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BACKGROUND Anecdotal reports suggest that the second trimester is the safest time to conduct a laparoscopic procedure on a pregnant patient, but this supposition has not been tested empirically. METHODS Previously instrumented preterm sheep (total n = 8) at gestational day 90 (term, 145 days) were

The addition of O2 to the CO2 does not prevent the systemic effects of the CO2 pneumoperitoneum in a rabbit model.

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CO2 pneumoperitoneum used in endoscopic surgery induces systemic effects by CO2 absorption. It was claimed that a reduction in CO2 pneumoperitoneum-induced metabolic hypoxemia was achieved by the addition of small amounts of O2 to the CO2 in a rabbit ventilated model. We reevaluated the effects of
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