retinoblastoma/bolesť hlavy

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13 výsledky

Uncommon presentation of pediatric ruptured intracranial aneurysm after radiotherapy for retinoblastoma. Case report.

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OBJECTIVE Radiation-induced intracranial aneurysms are a rare entity with high mortality. Their pathogenesis is still in debate. Their unique anatomy and behavior should be considered when deciding the proper management. A background of radiation, uncommon anatomic aspects, age of presentation, and

Incidence of pineal gland cyst and pineoblastoma in children with retinoblastoma during the chemoreduction era.

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OBJECTIVE To report on the frequency of cysts and tumors of the pineal gland in patients with retinoblastoma. METHODS Observational retrospective case control study. METHODS METHODS Institutional. study population: Four hundred eight patients treated for retinoblastoma from January 2000 to January

Metastatic patterns of retinoblastoma.

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Of 23 cases of metastatic retinoblastoma treated between 1922 and 1979, seven had metastases limited to the cranial vault and 13 had cranial metastases plus distant metastases. Globe pathology showed invasion of the optic nerve and/or the choroid in all but two patients, but was not predictive of

[Two cases of the middle fossa tumor following radiotherapy against retinoblastoma].

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Two cases of brain tumors which developed after radiotherapy against retinoblastomas are reported. A 17-year-old girl was admitted with a chief complaint of swelling in her forehead after head injury in July, 1981. At 7 months old her left eye had been enucleated and she had received radiation

Meningeal dissemination of retinoblastoma: CT findings in eight patients.

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Thirty-seven patients with retinoblastoma were evaluated prospectively by clinical examination, lumbar puncture, and CT. Eight (22%) of the 37 were found to have meningeal dissemination. The tumor was bilateral in three patients. Two cases showed no CT signs of local recurrence. Headache,

[Unusual presentation of retinoblastoma].

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Among the 185 retinoblastoma patients seen at the Lausanne Retinoblastoma Clinic from 1963-1993, 24 (14%) first presented with another sign than classical leukocoria (60.5%) or strabismus (21.5%). Most of these atypical signs were related to inflammatory complications of unrecognized retinoblastoma;

Spectral-domain optical coherence tomography and fundus autofluorescence features in a case of typical retinocytoma.

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OBJECTIVE To report spectral-domain optical coherence tomography (OCT) and fundus autofluorescence (FAF) features observed in a case of typical retinocytoma. METHODS Case report. RESULTS A 17-year-old girl on routine ophthalmologic evaluation for headache had an elevated translucent lesion with

Development of cyclin-dependent kinase modulators as novel therapeutic approaches for hematological malignancies.

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The majority of hematopoietic malignancies have aberrancies in the retinoblastoma (Rb) pathway. Loss in Rb function is, in most cases, a result of the phosphorylation and inactivation of Rb by the cyclin-dependent kinases (cdks), main regulators of cell cycle progression. Flavopiridol, the first cdk

Small molecule modulators of cyclin-dependent kinases for cancer therapy.

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The majority of human malignancies have aberrancies in the Retinoblastoma (Rb) pathway. Loss in Rb function results from the phosphorylation and inactivation of Rb by the cyclin-dependent kinases (cdks), main regulators of cell cycle progression. Thus, modulators of cdks may have a role in the

Pinealoblastoma with prominent retinoblastic differentiation: an unusual case in an adult.

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We present an extremely rare case of pinealoblastoma with retinoblastic differentiation in a 32-year-old woman who presented with a history of intermittent headache of 2 years duration and diminution of vision for 2 months which eventually lead to total loss of vision. The fundus examination showed

Atypical clinical presentation and long-term survival in a patient with optic nerve medulloepithelioma: a case report.

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BACKGROUND Medulloepithelioma is a rare congenital tumor of the primitive medullary neuroepithelium. A significant proportion of patients with medulloepithelioma arising from the optic nerve die from intracranial spread or cerebral metastasis. Because it has no known distinct clinical features and

Cerebral vasoconstriction triggered by sympathomimetic drugs during intra-atrerial chemotherapy.

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Reversible cerebral vasoconstriction syndrome is a rare cause of headache and stroke in the pediatric population. Reversible vasoconstriction is reported in a 19-month-old girl with retinoblastoma who underwent selective ophthalmic artery infusion chemotherapy with melphalan. Procedure-related

Signs and symptoms of childhood cancer: a guide for early recognition.

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Although cancer in children is rare, it is the second most common cause of childhood mortality in developed countries. It often presents with nonspecific symptoms similar to those of benign conditions, leading to delays in the diagnosis and initiation of appropriate treatment. Primary care

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