Dietary Arachidonic Acid, Obesity and Atopic Respiratory Disease
Ključne besede
Povzetek
Opis
Sixty young adult obese and non obese women, with, and without asthma, were studied using a cross-sectional design. Body composition was measured by plethysmography. A fasted blood sample was taken to measure: specific and total immunoglobulin (IgE) antibodies,biochemical markers of atopy; glucose and insulin to measure insulin sensitivity; estrogen(17β-estradiol) and sex hormone-binding globulin to measure estrogen status of the women; hormone-products of fat tissue ( leptin, adiponectin, resistin, tumor necrosis factor alpha (TNFα), interleukins (IL-6,IL-18), that have been associated with both obesity and immune processes involved in asthma and allergy. Dietary intake of omega 6: linoleic acid (LA), arachidonic acid(AA); and omega 3 fatty acids: α linolenic (ALA), eicosapentanoic (EPA) and docosahexanoic (DHA) and other nutrients were assessed by food frequency questionnaire.
Datumi
| Nazadnje preverjeno: | 06/30/2015 |
| Prvič predloženo: | 06/14/2015 |
| Predviden vpis oddan: | 08/12/2015 |
| Prvič objavljeno: | 08/16/2015 |
| Zadnja posodobitev oddana: | 08/12/2015 |
| Zadnja posodobitev objavljena: | 08/16/2015 |
| Dejanski datum začetka študija: | 09/30/2001 |
| Predvideni datum primarnega zaključka: | 04/30/2003 |
| Predvideni datum zaključka študije: | 04/30/2003 |
Stanje ali bolezen
Faza
Merila upravičenosti
| Starost, primerna za študij | 18 Years Za 18 Years |
| Spol, upravičen do študija | Female |
| Metoda vzorčenja | Non-Probability Sample |
| Sprejema zdrave prostovoljce | Da |
| Merila | Inclusion Criteria: - For asthmatics, only individuals that were willing and capable of not using asthma medications for two days prior to laboratory testing. Exclusion Criteria: - An individual was excluded from the study if she had a history of high blood pressure, diabetes, heart disease, cigarette smoking, or eating disorders. - Women that were pregnant or lactating. |
Izid
Primarni izidni ukrepi
1. Predictors of serum concentration of specific and total IgE antibodies in obesity [one day]
Ukrepi sekundarnega rezultata
1. Relationship between dietary levels of arachidonic, eicosapentanoic, docosahexanoic fatty acids and plasma concentration of leptin in obesity [one day]
2. Correlation between dietary arachidonic, eicosapentanoic,and docoshexanoic fatty acids and plasma concentration of adiponectin in obesity [one day]
