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Yoga for Chronic Chikungunya

Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Povezava se shrani v odložišče
StanjePrenehala
Sponzorji
Centre Hospitalier Universitaire de Pointe-a-Pitre

Ključne besede

Povzetek

The purpose of this study is to assess the benefits of a 8-week yoga program on quality of life in patients suffering from chronic chikungunya.
Studies have already shown the effectiveness of yoga practice on various arthralgia's, on the reduction of inflammatory reactions, on psychological disorders/sleep disorders and on quality of life. Considering quality of life as a global experience of balance between physical and mental wellbeing, the hypothesis was that the practice of yoga would globally improve the quality of life of patients with chronic chikungunya.

Opis

The chikungunya virus (CHIKV) is an arbovirus passed to humans by Aedes mosquitoes. Since its description in 1952, CHIKV has caused millions of human infections in Africa, the Indian Ocean islands, Asia, Europe and America (1). In total, since 2013, the epidemic has affected more than 2 million people in the Americas. In Guadeloupe, the emergence of chikungunya cases began in 2013. CHINKV was declared an epidemic in 2014 with an estimated 20,000 infected patients.Human infection with CHIKV is characterized by a sudden onset of severe joint pains, high fever and rash. The infection is self-limited and acute symptoms usually disappear within one or two weeks. However, this polyarthralgia is recurrent in 30 to 40% of infected people and can persist for years. Chikungunya is considered chronic if the symptoms persist after three months. The chronic stage can last from a few months to several years. Chronic chikungunya usually manifests as joint pain and stiffness, polyarthralgia (including rheumatoid arthritis, flare-ups of spondylitis), and other general symptoms such as intermittent headaches, edema, and paresthesia. The consequences of chronic CHIKV can be severe, with patients becoming maladjusted to their lifestyle, feeling weakened and diminished. Depression and medical leaves are very frequent, with many cases of disability. Yoga is an ancestral Indian practice aiming to connect the "body" and the "soul", the "self" and "the other". Traditionally, it is a philosophical way of living, sometimes combined with the practice of physical exercises. In westernized countries, Yoga is usually considered as a physical practice or an alternative therapy, using various techniques of breathing, relaxation and poses to release tensions and decrease pain.

Studies have already shown the effectiveness of yoga practice on various arthralgia's, on the reduction of inflammatory reactions, on psychological disorders/sleep disorders and on quality of life. Considering quality of life as a global experience of balance between physical and mental wellbeing, the hypothesis was that the practice of yoga, by improving these different aspects, would globally improve the quality of life of patients with chronic chikungunya.

Datumi

Nazadnje preverjeno: 06/30/2020
Prvič predloženo: 06/28/2020
Predviden vpis oddan: 06/30/2020
Prvič objavljeno: 07/01/2020
Zadnja posodobitev oddana: 06/30/2020
Zadnja posodobitev objavljena: 07/01/2020
Dejanski datum začetka študija: 10/02/2019
Predvideni datum primarnega zaključka: 03/29/2020
Predvideni datum zaključka študije: 03/29/2020

Stanje ali bolezen

Chikungunya Virus Infection

Intervencija / zdravljenje

Other: Wait-list control

Other: Yoga

Faza

-

Skupine rok

RokaIntervencija / zdravljenje
Experimental: Yoga
Yoga classes once a week for eight weeks
Other: Yoga
During 8 weeks, the intervention group attended weekly yoga sessions and had to practice poses at home
Other: Wait-list control
The delayed intervention group was to benefit from the intervention after week 8.
Other: Wait-list control
The wait-list group benefit from a 8-week yoga program after the interventional group

Merila upravičenosti

Starost, primerna za študij 18 Years Za 18 Years
Spol, upravičen do študijaAll
Sprejema zdrave prostovoljceDa
Merila

Inclusion Criteria:

- Patients suffering from chronic chikungunya, as documented by a positive chikungunya serology and the following symptoms: polyarthralgia and/or musculoskeletal disorder and/or morning stiffness.

- Patients had to be between 18 and 70 years old, and be

- patients affiliated to the French social insurance.

Exclusion Criteria:

- being pregnant;

- suffering from pre-existing rheumatic diseases before the Chikungunya infection;

- showing acute symptoms of a Chikungunya infection (documented serology);

- being unable to practice yoga poses ; having been recently treated with methotrexate or corticosteroids (less than 3 months ago);

- being under guardianship, trusteeship or legal protection,

- participating in another research study,

- showing severely impaired physical and/or psychological health, which in the opinion of the investigator, may affect the compliance of the study participant.

Izid

Primarni izidni ukrepi

1. Health Related Quality of Life - Short Form-36 (SF-36) [At baseline]

This scale measures eight health domains (Physical Functioning, Role-Physical, Bodily Pain, General Health, Vitality, Social Functioning, Role-Emotional, Mental Health) of quality of life for adults aged 18 and older. Using a scoring algorithm, the aggregated scores can provide two summary scores: the physical component summary (PCS) score and the mental component summary (MCS) score.

2. Health Related Quality of Life - Short Form-36 (SF-36) [after 8 weeks of intervention]

This scale measures eight health domains (Physical Functioning, Role-Physical, Bodily Pain, General Health, Vitality, Social Functioning, Role-Emotional, Mental Health) of quality of life for adults aged 18 and older. Using a scoring algorithm, the aggregated scores can provide two summary scores: the physical component summary (PCS) score and the mental component summary (MCS) score.

3. Health Related Quality of Life - Short Form-36 (SF-36) [after 18 weeks]

This scale measures eight health domains (Physical Functioning, Role-Physical, Bodily Pain, General Health, Vitality, Social Functioning, Role-Emotional, Mental Health) of quality of life for adults aged 18 and older. Using a scoring algorithm, the aggregated scores can provide two summary scores: the physical component summary (PCS) score and the mental component summary (MCS) score.

Ukrepi sekundarnega rezultata

1. nociceptive pain - Visual Analog Scale (VAS) [At baseline]

The Visual Analog Scale (VAS) is a 10 cm line with anchor statements on the left (no pain) and on the right (extreme pain). The patient is asked to mark their current pain level on the line. They can also be asked to mark their maximum, minimum, and average pain. The examiner scores the VAS by measuring the distance in either centimeters (0 to 10) or millimeters (0 to 100) from the "no pain" anchor point.

2. nociceptive pain - Visual Analog Scale (VAS) [after 8 weeks of intervention]

The Visual Analog Scale (VAS) is a 10 cm line with anchor statements on the left (no pain) and on the right (extreme pain). The patient is asked to mark their current pain level on the line. They can also be asked to mark their maximum, minimum, and average pain. The examiner scores the VAS by measuring the distance in either centimeters (0 to 10) or millimeters (0 to 100) from the "no pain" anchor point.

3. nociceptive pain - Visual Analog Scale (VAS) [after 18 weeks]

The Visual Analog Scale (VAS) is a 10 cm line with anchor statements on the left (no pain) and on the right (extreme pain). The patient is asked to mark their current pain level on the line. They can also be asked to mark their maximum, minimum, and average pain. The examiner scores the VAS by measuring the distance in either centimeters (0 to 10) or millimeters (0 to 100) from the "no pain" anchor point.

4. neuropathic pain- DN4 scale [At baseline]

The total score is calculated as the sum of the 10 items and the cut-off value for the diagnosis of neuropathic pain is a total score of 4/10.

5. neuropathic pain- DN4 scale [after 8 weeks of intervention]

The total score is calculated as the sum of the 10 items and the cut-off value for the diagnosis of neuropathic pain is a total score of 4/10.

6. neuropathic pain- DN4 scale [after 18 weeks]

The total score is calculated as the sum of the 10 items and the cut-off value for the diagnosis of neuropathic pain is a total score of 4/10.

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