Yoga for Chronic Chikungunya
Ključne besede
Povzetek
Opis
The chikungunya virus (CHIKV) is an arbovirus passed to humans by Aedes mosquitoes. Since its description in 1952, CHIKV has caused millions of human infections in Africa, the Indian Ocean islands, Asia, Europe and America (1). In total, since 2013, the epidemic has affected more than 2 million people in the Americas. In Guadeloupe, the emergence of chikungunya cases began in 2013. CHINKV was declared an epidemic in 2014 with an estimated 20,000 infected patients.Human infection with CHIKV is characterized by a sudden onset of severe joint pains, high fever and rash. The infection is self-limited and acute symptoms usually disappear within one or two weeks. However, this polyarthralgia is recurrent in 30 to 40% of infected people and can persist for years. Chikungunya is considered chronic if the symptoms persist after three months. The chronic stage can last from a few months to several years. Chronic chikungunya usually manifests as joint pain and stiffness, polyarthralgia (including rheumatoid arthritis, flare-ups of spondylitis), and other general symptoms such as intermittent headaches, edema, and paresthesia. The consequences of chronic CHIKV can be severe, with patients becoming maladjusted to their lifestyle, feeling weakened and diminished. Depression and medical leaves are very frequent, with many cases of disability. Yoga is an ancestral Indian practice aiming to connect the "body" and the "soul", the "self" and "the other". Traditionally, it is a philosophical way of living, sometimes combined with the practice of physical exercises. In westernized countries, Yoga is usually considered as a physical practice or an alternative therapy, using various techniques of breathing, relaxation and poses to release tensions and decrease pain.
Studies have already shown the effectiveness of yoga practice on various arthralgia's, on the reduction of inflammatory reactions, on psychological disorders/sleep disorders and on quality of life. Considering quality of life as a global experience of balance between physical and mental wellbeing, the hypothesis was that the practice of yoga, by improving these different aspects, would globally improve the quality of life of patients with chronic chikungunya.
Datumi
Nazadnje preverjeno: | 06/30/2020 |
Prvič predloženo: | 06/28/2020 |
Predviden vpis oddan: | 06/30/2020 |
Prvič objavljeno: | 07/01/2020 |
Zadnja posodobitev oddana: | 06/30/2020 |
Zadnja posodobitev objavljena: | 07/01/2020 |
Dejanski datum začetka študija: | 10/02/2019 |
Predvideni datum primarnega zaključka: | 03/29/2020 |
Predvideni datum zaključka študije: | 03/29/2020 |
Stanje ali bolezen
Intervencija / zdravljenje
Other: Wait-list control
Other: Yoga
Faza
Skupine rok
Roka | Intervencija / zdravljenje |
---|---|
Experimental: Yoga Yoga classes once a week for eight weeks | Other: Yoga During 8 weeks, the intervention group attended weekly yoga sessions and had to practice poses at home |
Other: Wait-list control The delayed intervention group was to benefit from the intervention after week 8. | Other: Wait-list control The wait-list group benefit from a 8-week yoga program after the interventional group |
Merila upravičenosti
Starost, primerna za študij | 18 Years Za 18 Years |
Spol, upravičen do študija | All |
Sprejema zdrave prostovoljce | Da |
Merila | Inclusion Criteria: - Patients suffering from chronic chikungunya, as documented by a positive chikungunya serology and the following symptoms: polyarthralgia and/or musculoskeletal disorder and/or morning stiffness. - Patients had to be between 18 and 70 years old, and be - patients affiliated to the French social insurance. Exclusion Criteria: - being pregnant; - suffering from pre-existing rheumatic diseases before the Chikungunya infection; - showing acute symptoms of a Chikungunya infection (documented serology); - being unable to practice yoga poses ; having been recently treated with methotrexate or corticosteroids (less than 3 months ago); - being under guardianship, trusteeship or legal protection, - participating in another research study, - showing severely impaired physical and/or psychological health, which in the opinion of the investigator, may affect the compliance of the study participant. |
Izid
Primarni izidni ukrepi
1. Health Related Quality of Life - Short Form-36 (SF-36) [At baseline]
2. Health Related Quality of Life - Short Form-36 (SF-36) [after 8 weeks of intervention]
3. Health Related Quality of Life - Short Form-36 (SF-36) [after 18 weeks]
Ukrepi sekundarnega rezultata
1. nociceptive pain - Visual Analog Scale (VAS) [At baseline]
2. nociceptive pain - Visual Analog Scale (VAS) [after 8 weeks of intervention]
3. nociceptive pain - Visual Analog Scale (VAS) [after 18 weeks]
4. neuropathic pain- DN4 scale [At baseline]
5. neuropathic pain- DN4 scale [after 8 weeks of intervention]
6. neuropathic pain- DN4 scale [after 18 weeks]