Chinese Journal of Natural Medicines 2012-Jan
A new eudesmane sesquiterpenoid lactone from Chloranthus japonicus.
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OBJECTIVE
To study the chemical constituents of the whole plant of Chloranthus japonicus.
METHODS
Compounds were isolated and purified by column chromatography. Their structures were elucidated on the basis of spectroscopic methods.
RESULTS
Six sesquiterpenoids were obtained and their structures were identified as chlojaponilactone A (1), atractylenolide III (2), neolitacumone B (3), 10α-hydroxy-1-oxoeremophila-7(11), 8(9)-diene-8, 12-olide (4), shizukanolide C (5), and shizukanolide H (6).
CONCLUSIONS
Compound 1 is a new eudesmane-type sesquiterpenoid lactone, and compounds 3 and 4 have been isolated from this species for the first time.
